Top 5 Contagion® News Articles for the Week of May 28, 2017
JUN 03, 2017 | CONTAGION EDITORIAL STAFF
This week’s top news articles highlighted research findings including that antibiotics fail to treat around 22% of adults with pneumonia. In addition, an ongoing outbreak of Mumps at the Pennsylvania State University that started in January has caused more than 80 illnesses. Amidst this, the US Food and Drug Administration approves a yellow fever vaccine for investigational use to be administered to travelers visiting yellow fever-endemic areas. And our top article for the week? Several outbreaks of norovirus that dominated schools in California, forcing some to close their doors
Read more about our Top 5 articles of the week:
#5: Researchers Identify Risk Factors for Antibiotic Failure Among Pneumonia Patients
The only guideline currently in place for the treatment and management of community-acquired pneumonia was published in 2007 by the American Thoracic Society and the Infectious Disease Society of America.
Now, new research shows that initial antibiotic therapy treatment fails in 1 in 4 adults with community-acquired pneumonia. The study was presented at the 2017 American Thoracic Society International Conference. The research group conducted the study with two goals in mind: to fill the gap left by the lack of “real-world,” large-scale data, which is needed to understand why antibiotics fail to treat infection in some individuals; and to identify ideal antibiotic choices for best treatment outcomes. The group collected data on more than 250,000 patients who presented with community-acquired pneumonia between 2011 and 2015. The average age among these patients was around 52 years, and most patients were female.
The authors defined treatment failure as: refilling the original antibiotic prescription, switching antibiotic regimen, hospitalization, or emergency room visits. Although treatment may have succeeded after patients were retreated (with another antibiotic or a second prescription of the same antibiotic), the researchers note that excessive use of antibiotics may lead to Clostridium difficile infection.
To read about the factors that increase the risk of treatment failure, click here.
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