Microbial count reduction of C. difficile
PCR ribotype 010 was the highest, no matter the disinfection method. This was followed by reduction of C. difficile
014 and then 027. The researchers concluded that the ribotypes 014 and 027 were more difficult to eradicate than type 010.
Type 027, in particular, is known for its “hypervirulence,” the study authors wrote, compared to 010 which does not produce toxins and does not trigger C. difficile
infection in humans. Ribotype 014 is the most prevalent (17%) PCR ribotype in the Netherlands, where the study took place.
The most effective disinfection method proved to be the hydrogen peroxide wipe, which even beat out the hydrogen peroxide spray. Additionally, the researchers found that wipes performed better than the sprays with the same active ingredient.
An argument could be made that using the sprays also included the use of paper towels for wiping the tiles, but the researchers cited another study which compared microfibers, cotton cloths, sponge cloths, and paper towels for their decontamination abilities and the researchers on that study did not find a significant difference.
There was a slight difference in relative light unit (RLU) reduction between the wipes and sprays: the wipes had a higher RLU reduction, but no significant different for RLU reduction was discovered between the 3 ribotypes.
“Impregnated cleaning / disinfection wipes generally outperform ready-to-use sprays, even if based on the same active ingredient, and should thus be preferred over sprays for the daily cleaning/ disinfection in rooms of patients with C. difficile infection,” the researchers wrote. “Future studies should use these more resilient types of C. difficile
to ensure the needed in vivo effect.”
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