SPOTLIGHT -
FDA Extends Johnson & Johnson COVID-19 Vaccine Shelf Life
The extension changes the shelf life from 3 months to 4.5 months.
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Senolytic Therapies May Reduce COVID-19 Mortality in the Elderly
The therapy was associated with reduced mortality, cellular senescence and inflammatory markers.
US, Pfizer-BioNTech Reach Agreement to Deliver Vaccine Doses to 100 Countries
The agreement brings the total number of doses bought by the United States to 800 million.
New International Travel Guidance Issued by the CDC
The public health agency eased travel recommendations for over 110 countries.
Plant-Based, Pescatarian Diets May Lessen COVID-19 Disease Severity
Diets consisting mainly of pants and fish were associated with lower chances of moderate to severe infections.
FDA Approves Pfizer’s 20vPnC Vaccine
The vaccine covers 13 S. pneumoniae serotypes plus an additional 7.
COVID-19 Causes More Complications in Youth Than Seasonal Flu
Pediatric patients with COVID-19 showed higher rates of symptoms than those with influenza.
Drop in Use of Convalescent Plasma Linked With Higher COVID-19 Mortality Rate
The therapy was associated with 95,000 fewer deaths through early March of 2021.
High Concentration of ACE2 in the Blood Linked With Risk of Severe COVID-19
High admission plasma ACE2 was associated with an increased maximal illness severity within 28 days.
Pfizer’s 20vPnC Vaccine Candidate Has FDA PDUFA Tuesday
The therapy builds on the Prevnar 13 platform with an additional 7 serotypes.
India Announces Centralized COVID-19 Vaccination Drive
Deaths continue to plunge in Brazil as more vaccinations are administered.
Alzheimer's Found to Increase Risk of Severe COVID-19
Regardless of age, Alzheimer’s was seen to be a risk factor for severe disease and death.
Smallpox Therapy Tembexa Approved by FDA
Tembexa was developed by Chimerix and showed a statistically significant survival benefit.
Obesity Linked to Increased Risk of long Term COVID-19 Complications
Those with moderate or severe obesity had a greater risk of hospitalization at 10-month follow up.
How the SARS-CoV-2 Virus Disguises Itself in the Body
Metal ions in the body help to form a bridge between viral mRNA and viral proteins.
COVID-19 Antibody May Help in Search for Broad-Acting Vaccine
Antibodies produced by memory B cells remembering an older infection could help develop new therapies.
Those Taking Anti-Inflammatories Do Not Respond as Well to COVID-19 Vaccine
Participants taking methotrexate for an immune disorder did not show an increase in CD8 T cells.
Therapy Discovered Which Blocks Multiple SARS-CoV-2 Variants
Mice treated with diABZI showed reduced weight loss and reduced viral load in the lungs and nostrils.
Mask Wearing, Physical Distancing Still Important During Vaccine Distribution
Maintaining non-pharmaceutical interventions were seen to reduce the spread of infections during computer modeling.
Vitamin D May Not Provide Protection Against COVID-19 Severity
No evidence of an association between genetically predicted vitamin D levels and COVID-19 susceptibility were found in the study.
COVID-19 Infection May Lead to More Severe Strokes
Younger participants in the study had a higher percentage of stokes than seen in the general population.
Inhalable Nanobodies May Prevent, Treat Severe COVID-19
Hamsters treated with the therapy did not lose any bodyweight and had reduced virus particles in their lungs.
Moderna Has Begun Seeking Full Approval For COVID-19 Vaccine
Worries mount in Africa as only 2% of the population has received a vaccine.
COVID-19 Increases Rate of Heart Attacks in Those With Genetic Risk
Rates of acute myocardial infarction were higher in those with genetic risks for familial hypercholesterolemia.
COVID-19 Mortality Associated With Easily Measurable Signs of Health
Patients with hypoxemia or tachypnea had an overall greater mortality risk compared to those without them.
Mild Case of COVID-19 Induces Antibodies With Lasting Protection
Participants with a prior case of disease showed cells in their bone marrow up to 4 months after their initial infection.
FDA Issues EUA to Monoclonal Antibody for Treatment of COVID-19
Sotrovimab was developed by GlaxoSmithKline and Vir Biotechnology to treat mild-to-moderate disease in adults and pediatric patients.
CDC Investigating Heart Inflammation in Teens Receiving COVID-19 Vaccine
Reports of myocarditis were reported in mostly young adult males, 4 days after administration.
Low Testosterone Puts Men at Higher Risk for Severe COVID-19
Lower levels of testosterone in the blood were also associated with increased inflammation.
Many Hospitalized COVID-19 Patients Discharged in Worse Physical Condition
Nearly half of COVID-19 patients never received rehabilitation evaluation and 20% lost daily living abilities.