What Are Pleuromutilin Antibiotics and How Do They Work?
JUN 08, 2017 | CONTAGION® EDITORIAL STAFF
Thomas File, MD, MSc, Chair of Infectious Disease Division, Summa Health in Akron, Ohio, explains what pleuromutilin antibiotics are and how they work.
Interview Transcript (slightly modified for readability):
“Pleuromutilins are a class of antimicrobial agents that have been recently developed for systemic administration for us to treat patients with certain infections. [They] work by inhibiting protein synthesis, but [they] have a unique mechanism of action which is different than other drugs that inhibit protein synthesis such that it is going to be effective against many pathogens that are resistant to these other drugs.”
DISCLOSURES: Dr. File is a consultant and on the Scientific Advisory Boards for Achaogen; Allergan; Bayer; Cempra; The Medicine’s Company; Merck; MotifBio; Nabriva; Paratek; Zavante.
To stay informed on the latest in infectious disease news and developments, please sign upfor our weekly newsletter.
HIV surveillance data is being used to populate an interactive map, capable of depicting the impact of HIV and mortality in the United States on national, state, and local levels.
Contagion® is a fully integrated news resource covering all areas of infectious disease. Through our website, quarterly journal, email newsletters, social media outlets, and Outbreak Monitor we provide practitioners and specialists with disease-specific information designed to improve patient outcomes and assist with the identification, diagnosis, treatment, and prevention of infectious diseases. Our mission is to assure that the healthcare community and public have the knowledge to make more informed choices and have a positive impact on patient outcomes.
2 Clarke Drive
Cranbury, NJ 08512