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A retrospective cohort study of more than 29 million patients found adults with prior semaglutide use had significantly lower 30-day mortality, hospitalization, and acute kidney injury after COVID-19 or influenza infection compared with a metformin comparator group.

Two Lancaster County residents have died from measles-associated complications, the state's first measles deaths in 35 years.

The phase 3 priMe trial found the investigational vaccine did not demonstrate noninferiority for preventing tuberculosis infection, though the study authors cited surrogate end point and exposure-imbalance issues that complicate interpretation.

Federal health officials are tracking simultaneous multistate outbreaks tied to frozen organic blueberries sold at Publix and alfalfa sprouts sold under the Calco and Everything Sprouts brands, together sickening more than 65 people across roughly 20 states.

Histoplasma, Blastomyces, and Coccidioides remain underrecognized causes of community-acquired pneumonia, particularly when clinical presentation mimics bacterial disease. Knowing where to look and when reshapes the diagnostic and therapeutic approach.

The US childhood vaccine schedule was the big news this month with the presidential executive order making changes to it as well as the latest Centers for Disease Control and Prevention kindergarten immunization numbers for the 2025-2026 year. Learn more about the news with clinician commentary and how it might impact patient care.

This week's top infectious disease stories cover treatment strategies for daptomycin-resistant Enterococcus faecium, fluoroquinolone prescribing's link to antimicrobial resistance, the legal standing of the childhood vaccine schedule executive order, and rising vaccine exemption rates alongside declining MMR coverage that's fueling continued measles outbreaks.

Newly released CDC data show childhood immunization rates have steadily declined since 2020, pushing measles vaccination coverage below the threshold needed for herd immunity and leaving an estimated 280,000 kindergartners without documented vaccinations this year. Robert Hopkins Jr, MD, medical director of the National Foundation for Infectious Diseases, discusses the latest vaccine data, geographic patterns, and how public health and school officials can address this continued trend.

Fluoroquinolone prescribing emerged as key driver of AMR in multiple pathogens in a 14-year study period at US Veterans Affairs medical centers.

With the news this week that childhood vaccine exemptions were at a historical high, it is important to understand what they are and how they are applied. Pediatrician Sharon Nachman, MD, offers some insights about the ability to forgo vaccines because of exemptions.

As of August 17, federal officials are reporting more than 15, 716 cases, hundreds of hospitalizations, and nearly all US states have been affected.

The latest national numbers show a decrease in vaccination rates, along with a spike in the number of immunization exemptions, leading to an increase in the number of cases for vaccine-preventable diseases such as measles.

In the second episode with Jason M. Goldman, MD, MACP, he touches upon the legal side of the order and how it may affect the childhood vaccine schedule.