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ViiV Healthcare's 2-drug Dovato regimen met its noninferiority end point against Gilead's 3-drug Biktarvy in the first head-to-head randomized trial comparing the 2 in treatment-naive adults with HIV.

As the Cyclospora outbreak continues, clinicians and public health advocates are highlighting a secondary risk: antibiotic treatment for the parasitic infection can disrupt the gut microbiome and raise the risk of C diff.

A study of 87 free-roaming New York City cats found 57.5% harbored at least 1 zoonotic endoparasite, with young male cats identified as Toxocara super-shedders depositing disproportionately high concentrations of roundworm eggs into urban soil.

A study in the American Journal of Physiology identifies retrotrapezoid nucleus (RTN) neurons as a critical and preserved circuit for counteracting opioid-induced respiratory depression, with optogenetic and chemogenetic stimulation of RTN neurons restoring breathing even during fentanyl administration.

Histoplasmosis is a widely distributed and often underdiagnosed fungal infection that can cause severe, sometimes fatal disease—especially in immunocompromised patients—due largely to persistent diagnostic delays and limited routine testing. Here is a review of diagnostics and treatment for the fungal infection.

The US has confirmed more measles cases in 2026 than in any year since 1991, with CDC and Johns Hopkins trackers both surpassing 2025's full-year total 5 months before year's end.

CDC's confirmed case count for the Cyclospora outbreak linked to Taylor Farms de Mexico lettuce has topped 4000 as FDA opens a second, separate outbreak investigation and lawmakers press for restored FoodNet surveillance.

Zoliflodacin has exhibited low cross-resistance with FQ-resistant and ceftriaxone- and azithromycinresistant in strains of N gonorrhoeae around the world. Here is a review of this recently approved antibiotic.

Basecamp Research's EDEN AI model, now integrated with Claude Science, designed antibiotic peptides active against 97% of WHO priority pathogens in lab tests, including MDR Acinetobacter baumannii, and can reduce vaccine target prioritization from weeks to a single AI conversation.

The FDA has granted EUA for the Allplex HSV-1&2/VZV/MPXV Assay (Seegene USA), the first multiplex PCR test designed to simultaneously differentiate HSV-1, HSV-2, VZV, and mpox virus from ulcerative skin lesions in a single run.

A study found that the investigational antiviral mosnodenvir reduced dengue virus infection RNA levels and symptoms in a controlled setting, supporting its potential as a prophylactic option.

Phase 3 ISLEND-1 and ISLEND-2 trials showed once-weekly oral islatravir/lenacapavir was noninferior to daily BIKTARVY and standard of care ART in maintaining virologic suppression at Week 48, with no new safety concerns identified.

A large platform trial evaluates diverse medications to relieve fatigue persisting post-acute COVID-19.