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CDC's confirmed case count for the Cyclospora outbreak linked to Taylor Farms de Mexico lettuce has topped 4000 as FDA opens a second, separate outbreak investigation and lawmakers press for restored FoodNet surveillance.

Zoliflodacin has exhibited low cross-resistance with FQ-resistant and ceftriaxone- and azithromycinresistant in strains of N gonorrhoeae around the world. Here is a review of this recently approved antibiotic.

Basecamp Research's EDEN AI model, now integrated with Claude Science, designed antibiotic peptides active against 97% of WHO priority pathogens in lab tests, including MDR Acinetobacter baumannii, and can reduce vaccine target prioritization from weeks to a single AI conversation.

A multicenter retrospective study found that the DENOVi clinical prediction score can safely help rule out infective endocarditis in patients with enterococcal bacteremia while reducing unnecessary echocardiography.

The FDA has granted EUA for the Allplex HSV-1&2/VZV/MPXV Assay (Seegene USA), the first multiplex PCR test designed to simultaneously differentiate HSV-1, HSV-2, VZV, and mpox virus from ulcerative skin lesions in a single run.

A study found that the investigational antiviral mosnodenvir reduced dengue virus infection RNA levels and symptoms in a controlled setting, supporting its potential as a prophylactic option.

Phase 3 ISLEND-1 and ISLEND-2 trials showed once-weekly oral islatravir/lenacapavir was noninferior to daily BIKTARVY and standard of care ART in maintaining virologic suppression at Week 48, with no new safety concerns identified.

A large platform trial evaluates diverse medications to relieve fatigue persisting post-acute COVID-19.

Although there has been conflicting public information around whether the source of the outbreak has been determined, Catherine O’Neal, MD, offers insights on key symptoms that warrant medical evaluation, what medical treatment may consist of for those being seen in an outpatient setting or those who are hospitalized, and considerations around eating produce.

The FDA has accepted Shionogi's supplemental New Drug Application seeking to expand the indication for cefiderocol (Fetroja) to pediatric patients with hospital-acquired and ventilator-associated bacterial pneumonia and complicated urinary tract infections caused by susceptible Gram-negative bacteria, with a regulatory decision expected in February 2027.

A multistate cyclosporiasis outbreak has sickened thousands of people across five states, prompting federal investigators to advise consumers not to eat shredded iceberg lettuce served at affected Taco Bell locations.

From the early days with no treatment, to AZT providing a lifeline, to today’s generation of antiretroviral therapies (ART), Perry N. Halkitis, PhD, MS, MPH, reminds people of how they have transformed the lives of people with HIV.

Kartik Cherabuddi, MD, FACP, FIDSA, provides insights on these aspects of the parasitic infection.