Investigational asuptegravir cut HIV-1 RNA by up to 2.36 log10 copies/mL in 10 days, and adding fostemsavir boosted CD4 gains in immunologic nonresponders.
|Videos|July 26, 2017
What is The Benefit of Darunavir Versus Other HIV Medications?
Author(s)Contagion Editorial Staff
Magda Opsomer, MD, explains why darunavir may be more beneficial than other HIV medications.
Advertisement
Magda Opsomer, MD, Director, Clinical Leader, Infectious Diseases and Vaccines, Janssen Pharmaceutical Companies, Belgium, explains why darunavir may be more beneficial than other HIV medications.
Interview Transcript (slightly modified for readability)
“Darunavir is a boosted protease inhibitor and what is special about it is that it has a very high genetic barrier to the development of resistance. [This] is very important when it comes to treating patients, because as we know, resistance makes it more difficult to treat patients at the end.”
Advertisement
Related to this article
Switching to once-daily bictegravir/lenacapavir kept adverse event rates similar to comparators and metabolic markers stable across comorbidity groups in ARTISTRY-1 and -2.
Karen B. Jacobson, MD, MPH, of Kaiser Permanente Northern California, presented data at IDWeek 2026 showing 58.2% of children younger than five years exposed to active hepatitis B in the home were exposed by someone other than their birth mother, a risk maternal screening alone would miss under the CDC’s revised birth dose recommendation.
The guidelines issued by the Department of Health and Human Services (HHS) have been updated with recent, evidence-based consensus of The Panel for the Use of Antiretroviral Agents in Adults and Adolescents.
In an ECOSPOR III analysis, all-cause hospitalization by week 4 fell to 3.4% with fecal microbiota spores vs 16.1% with placebo in recurrent C difficile infection.
Exploratory SCORPIO-PEP data presented at IDWeek 2026 show household contacts with breakthrough COVID-19 on ensitrelvir had lower peak viral RNA and fewer severe symptoms than placebo recipients.
Day 42 all-cause mortality was 23.8% with oral olorofim vs 24.3% with AmBisome plus standard of care in invasive aspergillosis unsuited to azole therapy.
MBL producers rose from 20.4% to 48.6% of US carbapenem-resistant Enterobacterales from 2021 to 2025, while aztreonam-avibactam stayed active against 97.7% of them.
Advertisement
Advertisement
Trending on Contagion Live
1
Cefiderocol-Xeruborbactam Active Against Carbapenem-Resistant Bacteria
2
Pritelivir Cuts Hospital Days in Refractory HSV in Phase 3 PRIOH-1
3
Zelicapavir Shortens RSV Symptoms Despite Missing Primary End Point
4
Measles Update: October 23, 2026
5