Rifaquizinone: A Novel Rifamycin-Quinolone Hybrid Antibiotic
April 28th 2025Rifaquizinone is a dual-pharmacophore antibiotic combining rifamycin and a fluoroquinolone-like compound, showing strong bactericidal activity against resistant Staphylococcus aureus strains and biofilms, with promising results for treating prosthetic joint infections (PJI) but limited oral bioavailability.
Decoding Malaria Parasites to Aid in Potential Treatments and Vaccines
April 25th 2025The Johns Hopkins Malaria Research Institute’s work in this area is looking to find ways to identify, for the first time, every single gene in the genome of malaria parasites, which could lead to the development of new treatments or vaccines.
CDC Reports 800 Confirmed Measles Cases Across the US, 624 Being in Texas
Published: April 23rd 2025 | Updated: April 23rd 2025Ninety-four percent of cases were tied to 10 outbreaks, Texas leading with 624 cases, while Michigan and Montana reported the first outbreaks since 2019 and 1990, respectively.
The Impact of the Pandemic on Antimicrobial Resistance
April 21st 2025A Centers for Disease Control and Prevention study looked at the COVID-19 pandemic's effect on hospital-onset infections. Study lead author Hannah Wolford offers insights on it, including what patient populations were most affected, and the significance of infection prevention strategies.
H5N1: The Outbreak the US Got Bored With
April 21st 2025Since its detection in early 2024, H5N1 has spread to dairy cows, poultry, and wild birds. Political factors, including leadership changes at the Centers for Disease Control and Prevention and cuts to public health resources, have worsened the situation, leading to a weakened response.