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Reported cases of Legionnaires’ disease have been on the rise for the past decade, and identifying Legionella bacteria requires specialized testing in the microbiology lab. Here is a clinical overview of Legionella bacteria, including required testing, treatment, and reporting to public health officials.

The 18-year old resident of the state suffered from acute disseminated encephalomyelitis. Pennsylvania numbers are surging with some of the highest state totals of measles cases in the country.

In its second disease cluster this summer, city officials are cleaning building towers in the South Bronx amidst an ongoing investigation and are rolling out measures to prevent future Legionnaires' cases.

The death was reported in Jefferson County where the coroner released a statement announcing it was in an unvaccinated woman.

Preliminary REMAP-CAP data suggesting oseltamivir may increase mortality in critically ill ICU influenza patients has sparked polarized reactions, but clinicians should await the full peer-reviewed manuscript before drawing broad conclusions, since the signal comes from a narrow, severely ill population and may reflect a therapeutic window effect rather than a blanket lack of efficacy.

The Vaccine Integrity Project, in collaboration with the American Medical Association, conducted a vaccine and immunization effectiveness and safety review for RSV, Influenza, and COVID-19 for the 2026-2027 season. JAMA published the review, and here is an overview of the data going into this year's seasonal respiratory virus season.

GSK will advance its investigational mRNA seasonal flu vaccine candidate, which targets both hemagglutinin and neuraminidase, into a phase 3 trial in September 2026 after the shot outperformed licensed flu vaccines in a phase 2 study.

Two Lancaster County residents have died from measles-associated complications, the state's first measles deaths in 35 years.

The phase 3 priMe trial found the investigational vaccine did not demonstrate noninferiority for preventing tuberculosis infection, though the study authors cited surrogate end point and exposure-imbalance issues that complicate interpretation.

A phylodynamic analysis combining Arizona wild bird surveillance with national sequence data found the H5N1 D1.1 genotype spread in a stepwise pattern among adjacent US flyways during fall 2024, with limited direct exchange between the Pacific and Atlantic flyways.

A serologic study of patients in northwestern Italy found hantavirus antibodies in 7.3% of samples tested, with neutralization data suggesting Puumala virus as the likely infecting strain in a region where rodent-borne viral infections are rarely diagnosed.

An oral antiviral candidate blocked airborne and direct-contact transmission of a measles-like virus in ferrets, offering a potential new outbreak-control tool as US measles cases hit a 35-year high.

Despite competing national crises drawing attention elsewhere, experts warn that the ongoing H5N1 avian influenza outbreak in birds, cattle, and humans in the United States highlights critical gaps in surveillance, worker protections, and pandemic preparedness that must be addressed to prevent a future pandemic.

Shionogi's XOCOVA (ensitrelvir) is now available in the United States as the first oral option to help prevent COVID-19 after exposure, following phase 3 SCORPIO-PEP trial data showing a 67% reduction in symptomatic infection risk.

A study in the American Journal of Physiology identifies retrotrapezoid nucleus (RTN) neurons as a critical and preserved circuit for counteracting opioid-induced respiratory depression, with optogenetic and chemogenetic stimulation of RTN neurons restoring breathing even during fentanyl administration.

The US has confirmed more measles cases in 2026 than in any year since 1991, with CDC and Johns Hopkins trackers both surpassing 2025's full-year total 5 months before year's end.

The FDA has approved an expanded indication for Merck's Capvaxive, allowing its use in children and adolescents aged 2 to 17 years with chronic medical conditions that increase their risk of pneumococcal disease following completion of a primary pneumococcal vaccination series.

The FDA has approved the first generic version of baloxavir marboxil (Xofluza), expanding access to a single-dose oral treatment and postexposure prophylaxis option for influenza in patients 5 years or older.

Invivyd has dosed the first participants in LIBERTY, a phase 3 trial comparing VYD2311 to an mRNA COVID vaccine and coadministration, as the BLA-enabling DECLARATION trial completes enrollment.

New phase 3 data from the SCORPIO-PEP study showed that a 5-day course of ensitrelvir significantly reduced the risk of symptomatic COVID-19 after household exposure, highlighting its potential to transform prevention strategies for high-risk populations and future variant-driven surges.

Real-world data suggest that 3 to 4 days of antibiotics can be as effective as 5 or more days in treating community-acquired pneumonia in hospitalized patients.

Results from a large population-based study found that receiving influenza and pertussis vaccines on the same day during pregnancy does not increase the risk of adverse maternal, birth, or neonatal outcomes compared with pertussis vaccination alone.

Study ascertains vaccination status of children hospitalized for Bordetella pertussis infections and assesses diagnostic value of testing modalities.

Study examines how clinicians consider rapid pneumonia panel test results in prescribing antibiotics in the ICU.

Investigators identified behavioral determinants of being tested for pathogen exposure, in interviewing a focus group presented with a hypothetical avian influenza outbreak.
























































































































































































