|Videos|July 31, 2020

Does Data Improve Vaccine Adherence?

What role does new research play in combating public vaccination concerns?

New data from an Israel-based team of investigators show the US Food and Drug Administration’s (FDA) pre- and post-market evaluations of new vaccine candidates has resulted in a largely sound and efficient system of regulation.

The findings, from Noam Tau, MD, of the Sheba Medical Center Department of Diagnostic Imaging, show that just 1 FDA-approved vaccine has been pulled from the market due to early detected safety concerns since 1996—while all other instances of post-approval safety outcomes were of little to no clinical impact on patients.

This new research comes on the heels of rapid progression of coronavirus 2019 (COVID-19) vaccine candidates, as well as recent polls and surveys showing a polarized public interest in receiving a potential COVID-19 vaccine or not.

Could data like that from Tau’s team persuade those who are still uncertain of vaccines? It depends, Tau told Contagion®.

“The big question is whether large population cares about facts, or scientific knowledge,” he said.

Luckily, Tau said in an interview with Contagion on the findings, a large portion of the population does endorse expert recommendations on vaccines. But even he and colleagues acknowledged the growing rate of those unwilling to vaccine—a trend which he noted has resulted in the return of previously rendered diseases, including measles.

A person’s unfamiliarity with an infectious disease, as well as a growing gamut of misleading information being shared, could make the unconvinced that much harder to convince, he said.

“You tell people to vaccinate their child against a disease they have never seen, and it’s quite hard for people to understand how and why they should give a drug to their child against a ghost,” Tau explained.


Related to this article

Pfizer 25-Valent Pneumococcal Vaccine Boosts Serotype 3 Response in Infants
Alejandra Gurtman, MD, discussed the phase 2 data at IDWeek 2026 which showed the investigational 25-valent pneumococcal conjugate vaccine 25vPnC produced serotype 3 antibody levels about 15-fold higher than Prevnar 20 after the booster dose, targeting a serotype still behind 10.6% of invasive pneumococcal disease in US children younger than five years.
Inhaled Amikacin Shows Low Resistance Rates in MAC Lung Disease in ENCORE
In the phase 3b ENCORE trial, adding amikacin liposome inhalation suspension (ALIS) to azithromycin and ethambutol significantly improved culture conversion in newly diagnosed MAC lung disease, while treatment-emergent amikacin (2.2%) and macrolide (1.1%) resistance stayed rare. Kevin Winthrop, MD, provides insights around the study.
Measles Update: October 30, 2026
The latest CDC numbers show a 5.8% increase in measles cases from week-to-week, bringing the 2026 US total to more than double the amount seen in all of 2025 with 2 months left in the year.
Cefiderocol Continues to Show Activity Against Resistant Gram-Negative Infections
Shionogi data presented at IDWeek 2026 demonstrated a 76.7% clinical response with cefiderocol in carbapenem-resistant respiratory infections and high in vitro activity against resistant P aeruginosa VAP isolates. Christine Slover, PharmD, vice president, Infectious Diseases US Medical Affairs, Shionogi, offers insights on the data as well as clinical considerations for providers when weighing the antibiotic for patients.