In the phase 3 LIBERTY study, the investigational monoclonal antibody, VYD2311, had significantly fewer adverse events than an mRNA COVID-19 vaccine, and it did not blunt vaccine-induced neutralizing titers when the two were given together.
|Articles|November 16, 2021
FDA May Authorize Pfizer-BioNTech COVID-19 Booster for All Adults This Week
Author(s)Kevin Kunzmann
A new report suggests FDA and CDC deliberations may result in booster doses of the mRNA vaccine becoming available by this weekend.
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The Food and Drug Administration (FDA) will likely authorize the
In news that coincides with an announced meeting of the Centers for Disease Control and Prevention (CDC) Advisory Committee for Immunization Practices (ACIP), regulators are anticipated to make BNT162b2 the first widely-available COVID-19 vaccine booster dose for fully-vaccinated adults with an emergency use authorization (EUA) and a possible supporting ACIP vote by the end of this week.
The EUA would allow for adults who received a second dose of the mRNA vaccine in the last ≥6 months to receive a booster dose as soon as this weekend. According to the report from The New York Times, Moderna is anticipated to also seek EUA approval for its booster dose of mRNA-1273 in all US adults in the near future.
Though experts have varied greatly on the utility and prioritization of COVID-19 vaccine boosters in differing adult populations, previous real-world data has supported the waning immunogenic effect of the 2-dose vaccine after 6 or more months of full vaccination. The 7-day US average of new COVID-19 cases has been steadily climbing since late October while full vaccination rate among the population has slowly climbed toward 60%.
“It’s time,” William Schaffner, MD, Professor of Preventive Medicine at Vanderbilt University Medical Center, told Contagion. “We’re ready for them, the public is ready for them, and providers are ready to recommend and give them.”
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