|Videos|November 25, 2017

Why the World Needs a C. difficile Vaccine

Richard Haupt, MD, MPH, explains why a vaccine to help prevent C. difficile is so needed.

Richard Haupt, MD, MPH, vice president of Medical Development at Pfrizer Vaccines, explains why a vaccine to help prevent C. difficile is so needed.

Interview Transcript (modified slightly for readability):

“C. difficile infection is a very important infection, and although there have been many, many [efforts] to try and prevent C. difficile acquisition of spores through infection control measures, and there have been many, many treatment modalities that have been developed for C. difficile infection, we continue to still see a significant amount of disease.

The Centers for Disease Control and Prevention recognizes C. difficile infection as an urgent public health threat. There are as many as close to 500,000 cases of C. difficile infection in the United States every year and close to 30,000 deaths that can be attributed, or at least associated with C. difficile infection. And so, it’s a significant disease state and a significant public health burden. And the vaccine that’s being developed is directed at toxins, and if that vaccine is successful, it can neutralize those toxins and [help] prevent C. difficile infection, and so, it would be an additional way in our public health armamentarium to be able to address C. difficile infection.”


Related to this article

Peggy Lillis Foundation Will Honor C diff Advocates at Annual Gala
The Peggy Lillis Foundation will host its 17th Annual Changing the Odds Gala this month in New York City, and it will include a casino, fellowship amongst the C diff community, and an award ceremony honoring a physician-scientist, philanthropist, a researcher, and a patient advocate for their contributions to C difficile awareness, treatment, and prevention.
Asymptomatic C difficile Colonization in Infants Doesn’t Mean Benign
A new study in infants challenges the long-standing belief about the pathogen’s effects in the youngest pediatric population. Senior author Joseph Zackular, PhD, provides insights around his work including how it reshapes gut development and offers potential intervention strategies to shield neonates.
How The Food Safety Surveillance Infrastructure Works in the US
In the first episode of our new series looking at the food safety network, Lynette Johnston, PhD, offers insights into how the federal government surveillance infrastructure operates and how epidemiologists serve as food detectives in determining bacterial pathogens and potential foodborne outbreaks.