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In 2018, the FDA approved omadacycline as a new oral/intravenous third generation tetracycline to treat Community Acquired Bacterial Pneumonia (CABP) and Acute Bacterial Skin and Skin Structure Infections (ABSSSI). Here is a clinical overview of omadacycline as well as recent phase 2 clinical trial results favoring oral omadacycline as an oral treatment option for Mycobacterium abscessus pulmonary disease.

The latest CDC numbers show a 5.92% increase of measles cases from week-to-week. This is a decrease in the percentage of cases from last week where there was a 9.18% increase.

The latest CDC numbers show a 9.18% increase of measles cases from week-to-week. This is an increase in the number of cases from last week where there was a 6.3% increase.

In this month's column, we look at the leadership change at CDC, an amicus brief supporting the AAP's lawsuit against HHS changes to the pediatric vaccine schedule, and potential clinical repercussions around the reports the federal government is considering removing the COVID-19 vaccine from the market.

The DOTS trial results found that although dalbavancin did not demonstrate superiority over standard intravenous therapy for complicated Staphylococcus aureus bacteremia, it was noninferior in efficacy, with similar safety, and offers a convenient 2-dose alternative that may reduce OPAT-related complications and health care utilization in select patients.

The Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices (ACIP) was supposed to convene this week to discuss COVID-19 vaccines. However, a district court’s decision to block recent vaccine policy changes has delayed the committee's meeting amid ongoing controversy over immunization guidance and rising public health concerns such as measles outbreaks. Here is some commentary on the inner workings of the current ACIP.