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The first patient was dosed for this open-label trial.

The FDA’s Vaccines and Related Biological Products Advisory Committee (VRBPAC) unanimously voted 2023-2024 COVID-19 vaccines should be updated to a monovalent XBB strain.

The American College of Physicians (ACP) CEO says it is important for physicians to move away from this traditional approach to transition to an empathetic style of discussion with patients so they can better relate and help those in need get back on track with their health post-COVID and schedule routine tests and immunizations.

With an estimated 30% of Americans living with a tattoo, the federal agency has developed guidance designed to give manufacturers information and resources to prevent potential health issues.

This model proposes a risk threshold for recommending rabies postexposure prophylaxis (PEP), potentially reducing unnecessary treatments and associated costs.

In phase 3 studies, the company’s investigational therapy, aztreonam-avibactam (ATM-AVI), had favorable results over other treatments used for complicated intra-abdominal infections (cIAI), hospital-acquired pneumonia (HAP), and ventilator-associated pneumonia (VAP).

"It does take the immune system a while to build up antibodies and recover," said Madeline King-Patel, PharmD, BCIDP, "So you don't want to give the vaccines too close to each other, or you're not going to get the full benefits."

The new guidelines for the first time offer guidance for patients who are not fully adherent to direct-acting antivirals.

As the first line of acute care, emergency departments are key stewards of antibiotics.

So far, the Virginia Mason Medical Center in Seattle has confirmed 33 patients have been infected with Klebsiella pneumoniae bacteria, 9 of whom have died.

A study of hospitalized patients with diarrhea found that collecting stool samples and testing all of them identified almost 30% more cases of C. diff than the standard of care.

In a guest commentary, Thelma Thiel, RN, Cofounder of The Liver Health Initiative provides a personal perspective on her son’s liver issues and the importance of why everyone should get tested for HCV.

Rates of hospital-onset multidrug-resistant P aeruginosa infections have increased significantly in recent years.

Metformin was shown to decrease the condition by 41%; whereas, ivermectin and fluvoxamine treatment did not see a clinical benefit.

The management of hospital-acquired pneumonia requires use of preventive bundles, mitigative of risk factors, and prompt diagnosis with initiation of treatment when highly suspected.

Due to worsening headaches and unrevealing cross-sectional imaging and ascites fluid analyses, this patient's differential evolved toward a central nervous system source.

Collaboration and teamwork are essential components in addressing UTI management and antibiotic resistance, explains infectious disease clinical specialist Kim Leuthner, PharmD, FIDSA.

This week's most-read story examined long COVID 2 years after acute infection. Read all about this and other infectious disease news now.

A new retrospective study found non-oxygen-dependent COVID-19 patients were more likely to experience this phenomenon if they were immunocompromised, receiving concomitant corticosteroids, or had comorbidities.

This new antiretroviral with a unique mechanism of action may be lifesaving for those with treatment-resistant HIV infection.

The investigational antibiotic, clovibactin, isolated from soil bacteria demonstrates unique mechanism against conserved site on drug-resistant bacteria.

COVID-19 reshaped the landscape of urinary tract infections (UTIs). Explore the prevalence of resistant pathogens, the impact on infection prevention, and the changes in positive pathogens.

After an all-day meeting, the FDA’s Antimicrobial Drugs Advisory Committee has voted to recommend nirsevimab (Beyfortus) for the prevention of respiratory syncytial virus (RSV) disease in infants.

The update includes several different infections, and offers brief descriptions of significant clinical trials, resistance mechanisms, and antimicrobial susceptibility testing methods for each of the pathogens.

New evidence suggests that oral transitional therapy may be a promising option for the treatment of infective endocarditis (IE). A retrospective cohort study reveals comparable clinical outcomes between oral and intravenous antibiotic regimens.

Cherokee Nation Health Services in Oklahoma found that 61% of patients diagnosed with HCV initiated care during the first five years of a program to eliminate HCV.

In this mini podcast, Kim Leuthner, PharmD, FIDSA, explores the challenges of choosing empirical therapy for complicated UTIs before culture results are available.

This study compares the mortality rates between Canada's public health care and the US private system, highlighting the complexities of pandemic response.

The Peggy Lillis Foundation (PLF) for C diff Education & Advocacy has been working to help people affected by the healthcare associated infection and getting involved with public advocacy including their support of the prospective antibiotic-related law, the Pasteur Act.

Unnecessary antibiotics for viral infections and incorrect prescriptions for bacterial infections have significant consequences, including increased adverse effects and healthcare expenditures.