Expert panelists provide insight on the relationship between the gut microbiome and c difficile, leading to the development of novel therapeutic approaches for infection.
EP. 1: C Difficile Infection: The Importance of the Gut Microbiome
Opening their discussion on Clostridioides difficile, experts provide an overview on the gut microbiome and colonization resistance.
EP. 2: C Difficile Infection: What Causes Disruption of the Gut Microbiome?
Shared insight on how disruption of the gut microbiome may occur based on antibiotic exposure, environmental factors, and diet.
EP. 3: Understanding How Disruption of the Gut Microbiome Leads to CDI
The panel reflects on how disruption of the gut microbiome leads to the proliferation of Clostridioides difficile.
EP. 4: Identifying CDI: Presentation, Prevalence, and Spectrum of Disease
Comprehensive discussion on the identification of Clostridioides difficile infection, the spectrum of disease, and overall epidemiology.
EP. 5: Who Is at Risk for Developing Clostridioides Difficile Infection?
An overview of the risk factors that contribute to the development of Clostridioides difficile infection in various health care settings.
EP. 6: Impact of Therapies on Clostridioides Difficile Infection Development
Experts review the impact that medications, antibiotic or otherwise, may have on the development of Clostridioides difficile infection.
EP. 7: Identification and Management of Recurrent C Difficile Infection
Shared insight on the prevalence of recurring Clostridioides difficile infection and management strategies.
EP. 8: Antibiotics for CDI: Administration Strategies and Treatment Guidelines
Experts consider optimal approaches to administering therapy for CDI and share insight on available treatment guidelines.
EP. 9: A Patient Case of C Difficile Infection: Selecting Optimal Therapy
Centering their discussion around a patient case of CDI, experts discuss optimal therapy selection given available agents and guidelines.
EP. 10: Selecting Therapy for Recurrent CDI: The Potential for FMT
The panel considers optimal therapy for recurrent CDI, particularly the role of fecal microbiota transplantation.
EP. 11: Addressing the Barriers to Fecal Microbiota Transplantation in CDI
Experts reflect on the barriers to utilizing fecal microbiota transplantation therapy in Clostridioides difficile infection.
EP. 12: Results of the PUNCH CD3 Trial: RBX2660 in Recurrent CDI
Shared insight on the phase 3 data behind RBX2660, a novel FMT therapy for patients with recurrent Clostridioides difficile infection.
EP. 13: Results of the ECOSPOR-III Trial: SER-109 in Recurrent CDI
The panel reviews phase 3 data behind SER-109, another novel FMT therapy for patients with recurrent Clostridioides difficile infection.
EP. 14: Practical Advice on Novel Fecal Microbiota Transplantation in CDI
Practical considerations for the future use of novel FMT therapy for patients with recurrent Clostridioides difficile infection.
EP. 15: Looking Toward the Future of CDI Management
Closing out their discussion on Clostridioides difficile infection, panelists share closing thoughts on novel pipeline therapies.
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