C Diff Update: The Latest News and Research

There has been some interesting news, research, and even federal legislation around this healthcare-associated infection. Read the latest on Clostridioides difficile (C diff) in the updates below.

Having an Infectious Disease Provider Follow C diff Patients Reduces Hospital Admission for Recurrence
A hospital CDI intervention program that supported patients via an ID specialist demonstrated clinical benefits compared to another hospital where patients were followed by providers of any specialty.

Making C diff a Nationally Notifiable Infectious Disease and Condition
A bill in the House of Representatives was just introduced with the advocacy of the Peggy Lillis Foundation in hopes of bringing more recognition and research to the healthcare-associated infection.

Are Probiotics Beneficial to Pediatric Population During Antibiotic Treatment?
A secondary analysis of a randomized trial points to limited benefits on the microbiota.

Investigational C Diff Therapy Shows Favorable Microbiome Characteristics, Phase 3 Trial Planned
In additional analyses, the novel antibiotic, ibezapolstat, demonstrated favorable gut microbiome changes including increased relative proportion of Actinobacteria in ibezapolstat-treated patients with C diff Infection (CDI).

Reducing Unnecessary C diff Tests Aids in Diagnostic Stewardship, Overtreatment

A Florida hospital takes a novel approach for the healthcare-associated infection and reduced inappropriate testing by setting up guidelines.