In the phase 3 LIBERTY study, the investigational monoclonal antibody, VYD2311, had significantly fewer adverse events than an mRNA COVID-19 vaccine, and it did not blunt vaccine-induced neutralizing titers when the two were given together.
News|Articles|September 10, 2026
FAQ: What You Need to Know About 2026-2027 COVID-19 Vaccines
FDA approved updated 2026-2027 COVID-19 vaccines from Pfizer-BioNTech, Moderna, and Novavax's partners, all reformulated to target the XFG variant, giving clinicians several options ahead of the fall respiratory virus season.
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The FDA approved multiple updated COVID-19 vaccine formulations for the 2026-2027 season in late August 2026, each engineered to protect against the currently circulating XFG variant or its JN.1-lineage subvariants.1-3 The approvals cover Pfizer and BioNTech's Comirnaty XFG, Moderna's Spikevax and mNEXSPIKE, and Novavax's partner-commercialized Nuvaxovid, spanning both mRNA and protein-based vaccine platforms.1-3 The clearances give clinicians several options ahead of the fall respiratory virus season, with indications concentrated among older adults and individuals with underlying conditions that place them at high risk for severe outcomes.1-3 FDA selected the XFG composition after identifying it as the preferred vaccine match for currently circulating SARS-CoV-2 strains in the United States, and shipping of the updated products was already underway or expected within days of approval.1-3
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The latest CDC numbers show a 6.2% increase of measles cases from week-to-week. Last week there was a 5.4% increase in cases showing a continuing steady increase dictated by ongoing outbreaks across the US.
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Vaxcyte's 31-valent pneumococcal conjugate vaccine candidate met every prespecified primary immunogenicity and safety endpoint against PCV20 and PCV21 in the OPUS-1 trial of 4,047 US adults.
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