Using Synergistic Combination Drug Therapy to Battle Antibiotic Resistance

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Edmond LaVoie, PhD, explains how his team’s approach can be applied in the development of novel drugs for the treatment of drug-resistant infections caused by Gram-negative and Gram-positive bacteria.

Edmond LaVoie, PhD, professor and chair, Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers University, co-founder of TAXIS Pharmaceuticals, shares how his team’s research on the development of MRSA prodrug, TXA709, can help inform the development of novel drugs to treat other drug-resistant bacteria. Dr. LaVoie explains the benefits of synergistic drug combination and how this allows for fewer possibilities for resistance to develop.

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