Articles by Carl V. Crawford, MD

Tips for Talking with Patients about Fecal Microbiota Transplant for Recurrent C. difficile Infections
ByPaul Feuerstadt, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Teena Chopra, MD, MPH,Matthew D. Sims, MD, PhD, FACP, FIDSA To close the discussion, experts on C. difficile infections discuss how they talk with patients about fecal microbiota transplantation.

Physicians’ Use of Fecal Microbiota Transplant for Recurrent C. difficile Infections
ByPaul Feuerstadt, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Teena Chopra, MD, MPH,Matthew D. Sims, MD, PhD, FACP, FIDSA Members of the panel discuss when and where they tend to utilize fecal microbiota transplantation for recurrent C. difficile infections in clinical practice.

Utilization of Fecal Microbiota Transplant Products in Clinical Practice
ByPaul Feuerstadt, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Teena Chopra, MD, MPH,Matthew D. Sims, MD, PhD, FACP, FIDSA Experts on the treatment of patients with C. difficile infections provide insights on the implementation of fecal microbiota transplant products into clinical practices.

Safety of Fecal Microbiota Options and Transfer of Food-Borne Allergens
ByPaul Feuerstadt, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Teena Chopra, MD, MPH,Matthew D. Sims, MD, PhD, FACP, FIDSA The panel provides insights on common adverse effects associated with fecal microbiota transplantation and analyzes the possibility of FMT products carrying pathogens or food-borne allergens.

ECOSPOR Trials and Data with Fecal Microbiota Spores, Live-BRPK Oral Capsules (VAS) for C. difficile Infections
ByPaul Feuerstadt, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Teena Chopra, MD, MPH,Matthew D. Sims, MD, PhD, FACP, FIDSA Paul Feuerstadt, MD, FACG, AGAF, discusses the key findings from the phase 3 ECOSPOR clinical trial for fecal microbiota spores, live-brpk oral capsules (VAS).

Data on Fecal Microbiota, Live-JSLM (RBL) for C. difficile Infections
ByPaul Feuerstadt, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Teena Chopra, MD, MPH,Matthew D. Sims, MD, PhD, FACP, FIDSA Sahil Khanna, MBBS, MS, discusses the effectiveness of live-JSLM (RBL) in preventing the recurrence of C. difficile infections.

Administration of FDA-Approved Fecal Microbiota Transplants for C. difficile Infections in Clinical Practice
ByPaul Feuerstadt, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Teena Chopra, MD, MPH,Matthew D. Sims, MD, PhD, FACP, FIDSA Matthew D. Sims, MD, PhD, FACP, FIDSA, discusses how fecal microbiota transplantation therapies are administered and shares his clinical experience.

Recent Fecal Microbiota Transplant Approvals for C. difficile Infections
ByPaul Feuerstadt, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Teena Chopra, MD, MPH,Matthew D. Sims, MD, PhD, FACP, FIDSA Carl V. Crawford, MD, provides a comprehensive overview of the two FDA-approved FMT therapies for patients with recurrent C. difficile infections.

Fecal Microbiota Transplantation for C. difficile Infections
ByPaul Feuerstadt, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Teena Chopra, MD, MPH,Matthew D. Sims, MD, PhD, FACP, FIDSA The panel review data from foundational studies on fecal microbiota transplantation in patients with C. difficile infections.

Contribution of Unnecessary and Prolonged Antibiotic Use to Recurrent C. difficile Infections
ByPaul Feuerstadt, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Teena Chopra, MD, MPH,Matthew D. Sims, MD, PhD, FACP, FIDSA A panel of experts on C. difficile infections discusses risks associated with antibiotic use, including vancomycin-resistant enterococci infections.

Managing C. difficile Infections in the Clinic
ByPaul Feuerstadt, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Teena Chopra, MD, MPH,Matthew D. Sims, MD, PhD, FACP, FIDSA Focusing on the treatment of patients with C. difficile infections, Carl V. Crawford, MD, provides clinical insights on medication tapering practices and therapies being utilized by clinicians.

Factors Contributing to C. difficile Infection Recurrence
ByPaul Feuerstadt, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Teena Chopra, MD, MPH,Matthew D. Sims, MD, PhD, FACP, FIDSA Matthew D. Sims, MD, PhD, FACP, FIDSA, discuss how antibiotics do not completely eliminate C. difficile infections, the drivers of recurrence, and new treatments that are addressing eubiosis and C. difficile spores.

Treatment Guidelines for C. difficile Infection
ByPaul Feuerstadt, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Teena Chopra, MD, MPH,Matthew D. Sims, MD, PhD, FACP, FIDSA Experts on C. difficile infections give an overview of the ACG and IDSA/SHEA treatment guidelines for initial infection, first recurrence, and subsequent recurrences.

Diagnostic Tests for C. difficile Infections
ByPaul Feuerstadt, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Teena Chopra, MD, MPH,Matthew D. Sims, MD, PhD, FACP, FIDSA Paul Feuerstadt, MD, FACG, AGAF, provides clinical insights on diagnostic testing practices for C. difficile infections, highlighting the EIA, GDH, and PCR assays.

Patients at Risk for Recurrent C. difficile Infections and the Role of Environmental Factors
ByPaul Feuerstadt, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Teena Chopra, MD, MPH,Matthew D. Sims, MD, PhD, FACP, FIDSA Sahil Khanna, MBBS, MS, outlines patients at risk for recurrent C. difficile infections, and Teena Chopra, MD, MPH, FACP, FIDSA, FSHEA, focuses on environmental considerations that can help prevent transmission.

Risk Factors for C. difficile Infections
ByPaul Feuerstadt, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Teena Chopra, MD, MPH,Matthew D. Sims, MD, PhD, FACP, FIDSA Carl V. Crawford, MD, outlines the risk factors for C. difficile infections, focusing on factors that affect the body’s microbiome or immune system, including antibiotics, age, comorbid conditions, exposures, and prior C. difficile infections.

Recurrence of C. Difficile Infections
ByPaul Feuerstadt, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Teena Chopra, MD, MPH,Matthew D. Sims, MD, PhD, FACP, FIDSA Teena Chopra, MD, MPH, FACP, FIDSA, FSHEA, and Matthew D. Sims, MD, PhD, FACP, FIDSA, provide clinical insights on the rate of recurrence of C. difficile infections and the impact on patients.

Epidemiology of C. difficile Infections in the US
ByPaul Feuerstadt, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Teena Chopra, MD, MPH,Matthew D. Sims, MD, PhD, FACP, FIDSA A panel of experts provide an overview of the epidemiology of Clostridioides difficile infections, highlighting diagnostic practices and the role of antimicrobial stewardship.

Looking Toward the Future of CDI Management
ByJames A. McKinnell, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Kelly R. Reveles, PharmD, PhD, BCPS Closing out their discussion on Clostridioides difficile infection, panelists share closing thoughts on novel pipeline therapies.

Practical Advice on Novel Fecal Microbiota Transplantation in CDI
ByJames A. McKinnell, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Kelly R. Reveles, PharmD, PhD, BCPS Practical considerations for the future use of novel FMT therapy for patients with recurrent Clostridioides difficile infection.

Results of the ECOSPOR-III Trial: SER-109 in Recurrent CDI
ByJames A. McKinnell, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Kelly R. Reveles, PharmD, PhD, BCPS The panel reviews phase 3 data behind SER-109, another novel FMT therapy for patients with recurrent Clostridioides difficile infection.

Results of the PUNCH CD3 Trial: RBX2660 in Recurrent CDI
ByJames A. McKinnell, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Kelly R. Reveles, PharmD, PhD, BCPS Shared insight on the phase 3 data behind RBX2660, a novel FMT therapy for patients with recurrent Clostridioides difficile infection.

Addressing the Barriers to Fecal Microbiota Transplantation in CDI
ByJames A. McKinnell, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Kelly R. Reveles, PharmD, PhD, BCPS Experts reflect on the barriers to utilizing fecal microbiota transplantation therapy in Clostridioides difficile infection.

Selecting Therapy for Recurrent CDI: The Potential for FMT
ByJames A. McKinnell, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Kelly R. Reveles, PharmD, PhD, BCPS The panel considers optimal therapy for recurrent CDI, particularly the role of fecal microbiota transplantation.

A Patient Case of C Difficile Infection: Selecting Optimal Therapy
ByJames A. McKinnell, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Kelly R. Reveles, PharmD, PhD, BCPS Centering their discussion around a patient case of CDI, experts discuss optimal therapy selection given available agents and guidelines.

Antibiotics for CDI: Administration Strategies and Treatment Guidelines
ByJames A. McKinnell, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Kelly R. Reveles, PharmD, PhD, BCPS Experts consider optimal approaches to administering therapy for CDI and share insight on available treatment guidelines.

Identification and Management of Recurrent C Difficile Infection
ByJames A. McKinnell, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Kelly R. Reveles, PharmD, PhD, BCPS Shared insight on the prevalence of recurring Clostridioides difficile infection and management strategies.

Impact of Therapies on Clostridioides Difficile Infection Development
ByJames A. McKinnell, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Kelly R. Reveles, PharmD, PhD, BCPS Experts review the impact that medications, antibiotic or otherwise, may have on the development of Clostridioides difficile infection.

Who Is at Risk for Developing Clostridioides Difficile Infection?
ByJames A. McKinnell, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Kelly R. Reveles, PharmD, PhD, BCPS An overview of the risk factors that contribute to the development of Clostridioides difficile infection in various health care settings.

Identifying CDI: Presentation, Prevalence, and Spectrum of Disease
ByJames A. McKinnell, MD,Carl V. Crawford, MD,Sahil Khanna, MBBS, MS,Kelly R. Reveles, PharmD, PhD, BCPS Comprehensive discussion on the identification of Clostridioides difficile infection, the spectrum of disease, and overall epidemiology.