Ha is an infectious diseases and antimicrobial stewardship pharmacist and program manager of antimicrobial stewardship in the Department of Quality at Stanford Health Care and lecturer in the Division of Infectious Diseases and Geographic Medicine at the Stanford University School of Medicine in California.
Obesity significantly impacts the pharmacokinetics (PK) of antifungal drugs like echinocandins, including volume of distribution (Vd) and clearance. However, despite these PK differences, current clinical evidence generally does not support the need for universal dose adjustments in obese patients. Clinicians should consider personalized dosing based on patient characteristics, infection severity, and specific drug properties due to echinocandins' favorable safety profiles.
There is value in leveraging the contributions of nurses, laboratorians, and informaticists in antimicrobial stewardship.
There is limited and conflicting data regarding the role of combination antifungal therapy for treatment of invasive mucormycosis.
Staff nurses are underused but potentially valuable contributors to antibiotic stewardship.
Published: November 18th 2024 | Updated: November 18th 2024
Published: April 23rd 2018 | Updated:
