
Non–carbapenemase-producing carbapenem-resistant Enterobacterales (CRE) isolates are the most common mechanism of CRE in the United States, but the optimal antimicrobial treatment remains to be elucidated.
Sunish Shah, PharmD, BCIDP, is a board-certified infectious diseases pharmacist at the University of Pittsburgh Medical Center. His research interests include management of drug-resistant bacterial infections, antimicrobial pharmacokinetics, and pharmacotherapy for the treatment of respiratory viruses.

Non–carbapenemase-producing carbapenem-resistant Enterobacterales (CRE) isolates are the most common mechanism of CRE in the United States, but the optimal antimicrobial treatment remains to be elucidated.

Here is a review the mechanisms that lead to resistance, including risk factors.

Published: October 20th 2021 | Updated:

Published: January 14th 2026 | Updated: