|Videos|October 4, 2020

How Will COVID-19 Vaccines Be Distributed and Stored?

A discussion with an expert on the particularities of the vaccines, which vary in temperature climate requirements and dosages.

As leading vaccine developers continue to collect phase 3 data for coronavirus 2019 (COVID-19) candidates, focus is beginning to turn from clinical effectiveness and safety toward vaccine prioritization and distribution.

How will the first regulated COVID-19 vaccines be managed and distributed?

In an interview with Contagion®, Lorne Clancey, senior director of temperature and environmental monitoring solutions at CenTrak, discussed an interesting facet of COVID-19 vaccine strategies: required storage temperatures for leading candidates.

“Some are going to require extreme cold—ultra-low temperatures, as a matter in fact, about minus-80 (Fahrenheit),” he said. “They have to be kept at this temperature to provide the necessary inoculation strength it has to deliver.”

Promising vaccines including the quartet of mRNA-based candidates from Pfizer and BioNTech would require dry ice use for storage and transportation, and space- and energy-consuming ultra-low units in hospitals and physician’s offices.

More is riding on the scientific community’s ability to cater to these specific needs than is discussed relative to the clinical data of the vaccines themselves.

“If the vaccine is compromised because of temperature, it’s not going to deliver the anticipated outcome, and that would basically mean the patient would have to come back and get it again,” Clancey said.


Related to this article

Inhaled Amikacin Shows Low Resistance Rates in MAC Lung Disease in ENCORE
In the phase 3b ENCORE trial, adding amikacin liposome inhalation suspension (ALIS) to azithromycin and ethambutol significantly improved culture conversion in newly diagnosed MAC lung disease, while treatment-emergent amikacin (2.2%) and macrolide (1.1%) resistance stayed rare. Kevin Winthrop, MD, provides insights around the study.
Measles Update: October 30, 2026
The latest CDC numbers show a 5.8% increase in measles cases from week-to-week, bringing the 2026 US total to more than double the amount seen in all of 2025 with 2 months left in the year.
Cefiderocol Continues to Show Activity Against Resistant Gram-Negative Infections
Shionogi data presented at IDWeek 2026 demonstrated a 76.7% clinical response with cefiderocol in carbapenem-resistant respiratory infections and high in vitro activity against resistant P aeruginosa VAP isolates. Christine Slover, PharmD, vice president, Infectious Diseases US Medical Affairs, Shionogi, offers insights on the data as well as clinical considerations for providers when weighing the antibiotic for patients.
Pfizer 25-Valent Pneumococcal Vaccine Boosts Serotype 3 Response in Infants
Alejandra Gurtman, MD, discussed the phase 2 data at IDWeek 2026 which showed the investigational 25-valent pneumococcal conjugate vaccine 25vPnC produced serotype 3 antibody levels about 15-fold higher than Prevnar 20 after the booster dose, targeting a serotype still behind 10.6% of invasive pneumococcal disease in US children younger than five years.