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New Study Shows High C. difficile Rates in Many US Hospitals

OCT 10, 2016 | EINAV KEET
While some may think of infectious diseases as a problem largely plaguing the developing world, antibiotic-resistant “superbugs” have shattered the notion that our modern, sparkling hospitals are so aseptic. Consumer Reports recently evaluated more than 3,100 hospitals in the United States and found that about a third of them received a low rating for controlling infections from Clostridium difficile.
While antibiotic medications are still hailed as important pathogen-stopping life savers, rapidly evolving “superbugs” are more resistant than ever to medical treatment, and the more antibiotics we throw at them the stronger the pathogens become. What were once powerful tools in public health now threaten to undo years of progress controlling infectious diseases. A 2013 report on antibiotic resistance threats from the Centers for Disease Control and Prevention (CDC) listed the 18 worst drug-resistant pathogens in the United States, and topping that list was C. difficile, and with good reason. Infections from these bacteria are an urgent threat to health, according to CDC studies, which show that the problem is only getting worse. The 2013 report estimated 250,000 C. difficile infections a year in the United States, but an updated study from 2015 found that Americans experience nearly half a million of these infections each year. Of those, approximately 29,000 patients die within 30 days of their C. difficile infection diagnosis, with some 15,000 deaths directly attributable to the infection.

The new Consumer Reports study highlights the issue of healthcare-associated infections, and how hospital patients receiving antibiotic medications continue to remain at high risk of developing C. difficile infections. More than half of all hospitalized patients receive an antibiotic at some point during their hospital stay, but up to 50% of these drugs prescribed in hospitals are given unnecessarily or inappropriately. Decreasing the use of antibiotics by 30% in hospital patients can reduce dangerous healthcare-associated C. difficile infections by more than 25%; therefore, there has been increased scrutiny in prescribing practices, due to drug-resistant infection rates in US hospitals.

The recent study focused on large teaching hospitals from around the country. Researchers found that 19 of these facilities had a low rating for preventing C. difficile infections, meaning that the hospitals had an infection rate worse than the national benchmark. Only two large teaching hospitals in the study received high scores, with C. difficile rates at least 50% better than the national benchmark. The ratings were measured based on data reported by hospitals to the CDC from October 2014 through September 2015, in teaching hospitals with at least 500 beds and 200,000 patient days to report during that period. Fifteen of the hospitals receiving low scores in preventing C. difficile had also received low scores six months earlier, although many scored much better on infection rates of methicillin-resistant staphylococcus aureus and other healthcare-associated infections.

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