An Estimated 5700 Zika Cases Went Unreported in 2017 Cuban Outbreak
Although Cuba reported no cases of Zika virus in 2017 and 2018, investigators used travel data and genomic epidemiology to uncover a large, “hidden” Zika outbreak.
Arizona's Maricopa County Reporting Record West Nile Virus Activity
West Nile virus cases have been relatively low overall this summer season but, following a wetter than usual season, Arizona has already seen 6 times the normal number of seasonal cases.
Investigators Discover a Soft Spot on Lassa Virus Surface
A research team’s latest study offers new insights into a weak point on the Lassa virus surface and the neutralizing antibodies capable of targeting it.
GLS-5300 MERS CoV Vaccine Candidate Shows Promise in Phase 1 Trial
Investigators in the first human trial of a MERS-CoV candidate report strong immune responses and no serious adverse events, advancing the vaccine candidate to phase 1/2a and phase 2 trials.
Healthy Gut Flora May Lower Risk of Infection Following Joint Replacement Surgery
Knee and hip replacement patients who have healthier intestinal microflora may have a lower risk of developing dangerous periprosthetic joint infections than patients with unhealthy guts.
European Syphilis Cases Up 70% Since 2010
A sharp increase in syphilis cases in Europe is hitting hardest among MSM and has been linked to the use of PrEP drugs and an increase in risky sexual behavior.
Baloxavir Shows Broad Antiviral Activity Against Influenza A, B, C, and D
In the wake of prior findings that influenza A viruses exhibited reduced susceptibility to single-dose baloxavir, a new study indicates that the antiviral medication inhibits all 4 types of flu, including viruses with pandemic potential.
Proactive WGS Offers a Cost-Effective Tool for MRSA Infection Control
Although conducting whole genomic sequencing creates an upfront cost in screening patients for MRSA, a new study finds that it’s a cost-effective way to prevent new infections and related deaths.
Study Identifies Therapeutic Ranges for Cefepime and Neurotoxicity Risks
One of the biggest studies to-date on the relationship between cefepime plasma concentrations and neurotoxicity has identified which patients are at greatest risk.
Trial Pairs PrEP With Behavioral Intervention to Prevent HIV in Drug Users
The program combines PrEP administration along with evidence-based behavioral intervention to reduce HIV risk behavior for HIV-negative, opioid-dependent people who use drugs and are receiving treatment.
Study: More Than 4 in 5 MSM on PrEP Have High-Risk HPV
Although PrEP drugs are key to preventing HIV infection, a new study by French investigators found a high prevalence of high-risk human papillomavirus infection among MSM taking PrEP.
TV Series Explores the Threat of a Next Global Influenza Pandemic
A recent 3-part series details the inevitability of another global influenza pandemic and how better surveillance and new vaccines may protect us in time for the next pandemic.
Reports of Expired Flu Vaccine Administration Comes as 2018-19 Doses Set to Expire
As injectable influenza vaccine doses from the 2018-19 season are set to expire on June 30, 2019, CDC investigators detail 192 cases of expired vaccine administration over the last year.
2019 Marks 2 Decades Since the Arrival of West Nile Virus in the US
With the arrival of summer in the United States, health officials are reminding the public to take precautions to avoid West Nile virus.
Study Identifies Risk Factors of Long-Term Mortality in Sepsis Survivors
A new study finds that age, sex, and site of infection can increase the risk of long-term mortality in the first 5 years following sepsis survival.
A Decade After the 2009 H1N1 Pandemic: Where Are We Now?
Health officials point to substantial progress in flu surveillance, treatment, and prevention; however, the global population remains vulnerable to new emerging viruses.
Study Finds Lower Than Expected Bone Density Loss in Regular PrEP Users
Although a new study finds that bone toxicities were lower than expected in PrEP users, investigators say that those at higher risk of bone fracture may want to seek PrEP alternatives once available.
Adult MSM PrEP Use May Help Lower HIV Prevalence in Adolescents
A new study combines models on PrEP use in both adult MSM as well as adolescent sexual minority males.
Number of Reported Polio Cases in First Months of 2019 Up From 2018
Following a rise in the number of wild poliovirus cases in Afghanistan and Pakistan from 2017 to 2018, a new report details the challenges in interrupting polio transmission.
Lower Humidity Linked to More Severe Flu Illness
A research team led by Yale University scientists report that breathing dry air lowers defenses against influenza virus infection.
Study Highlights Impact of CREs on Mortality and Hospital Stays in Lower-Income Countries
Few studies have examined the impact of CRE in low-income and middle-income countries, but now new literature provides much-needed data on antibiotic resistance in these settings.
Prophylactic Antibiotic Reduces Risk of Infection by 56% Following Operative Vaginal Birth
Although antibiotic prophylaxis for new mothers is common following caesarean section births, a new study provides evidence of benefits on infection reduction in women following operative vaginal birth.
Study Investigates Quality of Generic PrEP Drugs Available Online in the UK
Generic PrEP drugs offer a cost-effective way for people to reduce their risk of HIV, though some worry about the authenticity of drugs purchased online.
CAL02 Treatment Could Be Breakthrough for Severe Pneumococcal Pneumonia
In a new study, patients receiving CAL02 had faster clinical improvement, including faster resolution of organ dysfunctions, as well as more rapid clearance of pneumonia, when compared with placebo.
Investigators Discover Unknown Achilles Heel of Influenza Virus
In an unexpected discovery, a NIAID-funded study team has found that a human antibody can target a part of the hemagglutinin protein that the influenza virus uses to enter and infect cells.
2019 Fluoroquinolone Breakpoints Revised for Enterobacteriaceae and Pseudomonas aeruginosa
A revision to the fluoroquinolone antimicrobial susceptibility testing breakpoints for 2 bacteria comes following evidence that previous breakpoints were too high to detect low-level antibiotic resistance.
NIAID to Give $41.6 Million in Funding for Development of STI Vaccines
Following a rise in sexually transmitted infection diagnoses in recent years, NIAID is awarding grants for research into syphilis, gonorrhea, and chlamydia vaccine candidates.
CDC Reminds Americans Traveling Abroad of the Dangers of Rickettsiosis From Ticks, Fleas, and Chiggers
Ahead of the summer travel season, the CDC is reminding Americans traveling abroad to be aware of tickborne rickettsial diseases.
Study Finds 32 Predictors of C Diff Infection Recurrence
The authors of a new study say the use of antibiotics and proton pump inhibitors are among the list of risk factors for recurring C diff infections.
Candida and C Diff: Rise in Coinfections Could Be the Next Big Health care-Associated Concern
A new review recommends updated guidelines for diagnosing and managing Candida and C diff coinfection.
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