Alexandra Ward

The research team deciphered that the nitazoxanide boosts the ability of specific viral sensors to detect Ebola when infected, which then sparks an antiviral immune response.

Blocking the transport of critical metals like zinc into the cell could be a way to prevent growth and therefore infection by Neisseria gonorrhoeae.

Investigators exposed 6 genetically distinct, clinically relevant methicillin-resistant S aureus isolates to cigarette smoke to analyze how this contact altered specific virulence phenotypes.

When speaking with patients or parents, it is important for health care practitioners to stress that vaccines are safe, and vaccines save lives.

The adjusted hazard ratios for 1-dose and 2-dose recipients were comparable to the 3-dose recipients (1 dose 1.01 [95%CI 0.81–1.26], 2 doses 1.00 [0.85–1.17]) after adjusting for age at vaccination among the vaccinated group.

The percentage of participants who achieved HIV-1 RNA< 50 copies/mL in the 0.25 mg, 0.75 mg, 2.25 mg MK-8591 dose groups was 89.7%, 90.0%, and 77.4%, respectively, at week 48.

At week 48, 83.8% of participants in the TAF/FTC/DTG arm had HIV RNA < 50 copies/mL, 84.9% for TDF/FTC/DTG and 78.6% for TDF/FTC/EFV.

The final results of HOPE, a phase 3 open-label extension trial, show high uptake and lower-than-anticipated HIV-1 incidence.

With 1329.6 person-years of PrEP use accumulated, early continuation was achieved by 79.8% of participants.

The phase 2a study compares a bivalent combination of Clade C and Mosaic gp140 with a single-valent Clade C gp140.

A handful of new studies weighing the risks and benefits of ART regimens containing dolutegravir have triggered new recommendations from the WHO.

The difference between NTD prevalence with dolutegravir and non-dolutegravir antiretrovirals from conception was small, but significant at 0.20% difference (95%CI 0.01%, 0.59%).

A 10-minute cycle of PX-UV light on glass slides inoculated with C auris reduced the number of colony forming units per milliliter by 99.6%.

Investigators detected HIV DNA in the cerebrospinal fluid of 48% of participants, which was linked to worse neurocognitive outcomes.

Mosaico plans to register 3800 HIV-negative participants aged 18 to 60 years when enrollment opens later this year.

PrEP awareness among these MSM rose from 60% to 90% from 2014 to 2017, and PrEP use increased from 6% to 35%.

Of the 216 infants studied, 31.5% had delayed neurodevelopment and/or eye abnormalities and/or hearing deficits when evaluated as late as 32 months of age.

Investigators sought to identify potentially intervenable factors that affect mortality among PLWH in the city of San Francisco.

Read Contagion®’s full Q&A with Dr. Drew Pinsky on the explosion of infectious diseases on the Pacific Coast tied to the humanitarian crisis there.

There have been 32 confirmed cases of the rare bacterial infection in southeastern England’s Mid Essex, mostly among elderly individuals receiving chronic wound care.

The FDA approved the first darunavir-based single-tablet regimen for the treatment of HIV in July 2018. How is it working out for patients and providers alike?

The research team used single site testing for 1442 (32%) patients with 54 positive (4%) results. Multiple site testing was performed on 3037 (68%) patients and 255 (8%) were positive from at least 1 site tested.

De-escalation to monotherapy upon bacteremia resolution did not result in unfavorable outcome differences compared with those who continued combination therapy.

Spurred by an increasing population of homeless individuals and a waning vaccination rate, Los Angeles is teetering on the brink of an infectious disease emergency.

The cases are concerning, especially after 1 death was reported in 1 of the infected individuals, although it’s not clear whether the rare tick-borne Powassan virus was directly responsible.

EMS practiced hand hygiene before patient contact in just 7% of assessments but wore gloves in 100% of observed interactions

A new study investigates the association of S aureus colonization with specific Immunoglobulin E production with common food allergens and allergies in early childhood independent of eczema severity.

The American Society of Transplantation Infectious Diseases Community of Practice has issued a new section of guidelines as part of its series of evidence-based graded recommendations for the diagnosis, prevention, and management of SSIs.

A recent study found that at the 18-month mark, PLWH on dolutegravir gained 6.0 kg compared with 2.6 kg for NNRTI (p

The adjusted odds for having oropharyngeal gonorrhea were 1.46-fold for men with ≥4 kissing-only partners and 1.81-fold for men with ≥4 kissing-with-sex partners.