SPOTLIGHT -
Hospitals Finds Low Rates of Asymptomatic Toxigenic C difficile Carriage
The study was designed to help scientists better understand how to prevent in-hospital transmission of C difficile.
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Key Differences Found in Microbiomes of Patients
The study is believed to be the first to examine such a broad array of patient groups.
Interspecies Interactions in Gut Affect C difficile’s Antibiotic Susceptibility
Competition among species has therapeutic implications, the authors found.
IDSA, AASLD Hepatitis C Guidelines Offer Strategies for Incomplete Adherence
The new guidelines for the first time offer guidance for patients who are not fully adherent to direct-acting antivirals.
Mother-to-Child Hepatitis B Transmission Presents Economic Trade-Offs
Expanding peripartum prophylaxis could be more cost-effective, but would likely lead to significant over-treatment.
Study: AAV2 May Play Role in Pediatric Hepatitis Cases of Unknown Etiology
Investigators found most cases were infected with adeno-associated virus 2 and a helper virus, though it’s unclear what role the former plays.
Uptick in rCDI Coincided with COVID-19, According to New Analysis
Data from New Haven County, Connecticut, suggests the pandemic might have hurt efforts to curb recurrent CDI.
CDI Remains a Major, ‘Multifactorial’ Challenge
While efforts to curb in-hospital infection seem to have paid off, community-acquired cases appear headed in the opposite direction.
Higher Uptake of Paxlovid Could Dramatically Reduce Hospitalizations, Deaths
Simulations suggest deaths from COVID-19 could be cut in half if 80% of eligible patients took the antiviral therapy.
CDI Risk Higher for People with COVID-19
The investigators found the risk of hospital-acquired Clostridioides difficile (CDI) infection increased when a hospital switched to serving only coronavirus disease 2019 patients.
Access Point Choice, Sociodemographic Factors Affect S Aureus Risk in Hemodialysis
Higher poverty, crowding, and lower education levels disproportionately increased a person’s risk of S aureus infection, according to a new study.
4CMenB Vaccination Leads to Strong Protection in Children 5 and Under
The vaccine even provided significant protection when children had just one dose, investigators found.
Key Long COVID Symptoms Persist for Nearly 2 Years, But Many Return to Work
A new report tracking patients suggests that even those who return to work experience persistent symptoms.
Study Identifies Links Between Gut Dysbiosis and COVID-19
The data may help explain why COVID-19 patients experience dangerous secondary infections.
Significant Barriers Keep Patients from Adopting Injectable PrEP
The study showed, however, that physicians can help solve the problem if they are willing to answer patient’s questions about the therapy’s efficacy and safety.
Vitamin D Supplementation Appears to Offer Protective Benefits Against COVID-19
A new report finds veterans who took vitamin D supplements were less likely to get COVID-19 and less likely to die within 30 days of infection.
Measuring Disease Severity, Quality of Life in Japanese Hepatitis Patients
As viral hepatitis is the most common blood-transmitted infection globally, assessing the toll of hepatitis and hepatitis-related conditions is critical.
GSK Halts Trials of new UTI Treatment Gepotidacin for Efficacy
The company says it plans to begin talking with regulators next year after seeing positive efficacy data in the trials.
CDI Biotherapeutic RBX2660 Outperforms Placebo in Phase 3 Trial
The closely watched therapeutic candidate led to long-term responses in 90% of patients who benefited from the therapy.
By Raising Awareness of C diff, Foundation Hopes to Minimize Risk
November is Clostridioides difficile (C diff) awareness month. The Peggy Lillis Foundation hopes to use the month to increase the public’s awareness of the dangers of the infection.
Hepatitis A Vaccination Program Works, But Migration Complicates Impact
Over the past decade, the number of cases of hepatitis A infection at a Turkish hospital has decreased, but a growing proportion of cases come from migrants to the country.
Among People with Hemophilia, HCV Prevention is Working, But Eradication Remains Elusive
A new review article suggests it is possible to eradicate hepatitis C virus infections among people with hemophilia, but it will take intense focus from public health agencies.
Bivalent SARS-CoV-2 Vaccine Might Offer Better Omicron Protection
Interim data show a bivalent vaccine that contains the Omicron variant may be more effective.
HIV Prevalence High Among Female Sex Workers But Interventions Have Positive Effect
There are a number of programs designed to help lower rates of infection and transmission amongst this industry's workforce in South Africa.
Causation Prediction Tool May Lower Rates of Pediatric Antibiotic Prescriptions for Diarrhea
When physicians were told that a case was likely viral they were less likely to prescribe antibiotics, a new study shows.
Most People with HCV Infection Are Not Treated with Direct-Acting Antivirals
A new report underscores a persistent problem of patients not receiving antivirals despite their high curative rate.
Report Finds "Mix-and-Match" COVID-19 Booster Approach More Effective
People who initially received an mRNA vaccine but were boosted with the Janssen vaccine had superior immune responses, the study found.
HIV Associated with Rapid Age Acceleration, New Study Finds
The study was longitudinal in nature, comparing at-risk people who became infected with HIV to at-risk people who did not.
Regular COVID-19 Screening in Schools Can Control Infections, Limit Closures
The model suggests screening unvaccinated students could reduce absences by 80% compared to reactively closing classes with infected students.
Report: COVID-19 Had Dramatic Effect on Life Expectancies of Poor and Minorities
Though all racial and ethnic groups saw declines in life expectancy, the impact was greater among members of minority groups.