Similar to HIV, the colonial and postcolonial history is fundamental to the biology of this monkeypox outbreak.
In the latest Bench to Bedside column, clinicians provide information and resources on recommended topics learners should explore.
Implications for antimicrobial use and antimicrobial resistance.
As with other metallo-β-lactamases, NDM is capable of hydrolyzing nearly all β-lactams, including carbapenems, and the search for the proper antimicrobials is challenging.
Kevin Nguyen, PharmD, offers some insights on some of the challenges in the outpatient setting with regards to stewardship, and novel strategies being utilized.
Two RSV vaccines for seniors were FDA approved this year and here is an overview of the vaccines and the study data.
Vaccination for VZV and HPV requires special consideration in immunocompromised patients. They are at risk for more severe viral illnesses if not immune, but they may also have decreased response to, and increased adverse effects from, vaccines.
The ideal parameter for vancomycin monitoring is the area under the curve, which can be calculated using pharmacokinetic equations or Bayesian software.
This crisis has united multidisciplinary groups and laid the foundation to better equip the health care workforce for future pandemics.
A preview of our August 2021 issue Chairman’s Letter.
The ideal parameter for vancomycin monitoring is the area under the curve, which can be calculated using pharmacokinetic equations or Bayesian software.
This novel therapeutic option represents the first long-acting injectable approved for maintenance of HIV-1 suppression.
PEN-FAST is a validated risk stratification tool that promotes efficient, safe, and effective de-labeling of penicillin allergies.
Both undertreatment and overtreatment were common in this cohort of penicillin-allergic pregnant women with Group B Streptococcus (GBS).
Gender-affirming hormone therapy (GAHT) therapy consists of administration of exogenous hormones and suppression of endogenous hormone production, with the goal of obtaining characteristics more congruent with an individual’s gender identity. Here is a review of these therapies and consideration for PrEP and the risks associated with HIV in this diverse population.
A study of carbapenemase-producing organisms found similar rates of infections, highlighting treatment challenges, the role of rapid diagnostics, and surveillance on antimicrobial stewardship due to high mortality rates.
This form of stewardship can reduce unnecessary antibiotic prescribing, reduce costs, and optimize patient outcomes.
The need for safe and effective treatment against the various strains of COVID-19 increase, and investigators continue to assess various pharmacologic options.
There has been an emergence of extracorporeal membrane oxygenation-associated infections. Here is a review of how to define them and clinical management of this heterogeneous syndrome.
The healthcare sector currently faces an unmet need in treating herpesviruses, hepatitis B, and hepatitis D, which could significantly improve patient outcomes. Addressing this involves considering the necessary steps and understanding the challenges pharmaceutical companies encounter as they work towards developing treatments for these conditions.
Changes in microbiology and antimicrobial resistance patterns warrant reevaluation of our current therapies for this condition.
Clinical and public health laboratories reported increased influenza virus detections over the past few weeks, but US cases remains comparatively low to previous flu seasons.
Deborah Birx, MD, and Amy Carenza, BBA, highlight the targeting of multidrug-resistant organisms and tracking of infection trends without increasing staffing needs.
This study characterized the incidence of serotonin syndrome and identified contributing risk factors with combined medications for opioid use disorder (MOUD) and linezolid use.
Important clinical considerations to know about resistant CMV infections.
The limitation in the number of pediatric-specific guidelines by professional organizations, and results from large randomized clinical trials, may place an additional emphasis on literature evaluation skills for pediatric ASP pharmacists.
By addressing ART-related medication errors and increasing linkage to care, antiretroviral stewardship programs can improve management of inpatients with HIV.