Logo Image
|Videos|June 23, 2020

Contagion Live News Network: Pneumococcal Conjugate Vaccine V114

An overview of today's top infectious disease stories.

Investigational PCV Meets Safety and Immunogenicity Objectives in Initial Phase 3 Studies

Merck has announced results from 2 initial Phase 3 studies, PNEU-FLU and PNEU-WAY, evaluating the firm’s 15-valent pneumococcal conjugate vaccine (PCV).

V114 uses pneumococcal polysaccharides from 15 serotypes conjugated to a CRM197 carrier protein, including serotypes 22F and 33F. These serotypes are widely associated with invasive pneumococcal disease globally and are not found in the currently licensed pneumococcal conjugate vaccine for adults.

“Certain populations are at greater risk for pneumococcal disease, reinforcing the importance of investigating new interventions focused on their specific needs,” said Luwy Musey, MD, executive director in biologics, vaccine clinical research, at Merck Research Laboratories. “Results from these first two Phase 3 studies of V114 are encouraging and we look forward to sharing additional data in the future from our ongoing clinical development program, including our pivotal studies assessing the immunogenicity of V114 and its potential to protect against the serotypes most likely to cause invasive disease.” Read more.

CONTAGION LIVE NEWS NETWORK - JUNE 23, 2020:

(Assistant Editor Grant Gallagher gives an overview of the day's top stories.)

Related to this article

View more
Measles Update: October 16, 2026
Measles Update: October 16, 2026
The latest CDC numbers show an 8.1% increase in measles cases from week-to-week, bringing the 2026 US total to 4410 confirmed cases. A CDC disease detective is going to Pennsylvania to aid in the state's massive outbreak, and the agency reports on a rare measles complication that is uniformly fatal.
Read more
NFID Survey Finds Respiratory Vaccine Gap Driven by Lack of Clarity, Not Hesitancy
NFID Survey Finds Respiratory Vaccine Gap Driven by Lack of Clarity, Not Hesitancy
The National Foundation for Infectious Diseases (NFID) recently held its respiratory season kick-off, which included the release of its annual respiratory disease survey. This year, the survey revealed the gap between vaccine support and uptake. Robert Hopkins Jr, MD, medical director of NFID delves deeper into the findings of the survey and the vaccine uptake challenges associated with certain immunizations.
Read more
Measles Update: October 9, 2026
Measles Update: October 9, 2026
The latest CDC numbers show a 5.0% increase of measles cases from week-to-week. The US total reached 4080 confirmed cases, 78% above all of 2025.
Read more
FAQ: What You Need to Know About Measles in 2026
FAQ: What You Need to Know About Measles in 2026
With US measles cases nearing 3,900 this year and Pennsylvania reporting its fifth measles-related death, here is a review of how the virus spreads, how it is prevented and managed, and what severe disease looks like.
Read more