What You Need to Know
Alcohol-related hepatitis is a major liver disease that causes substantial morbidity and mortality, leading to a significant healthcare and economic burden, not only in the United States but on a global scale.
Neutrophils, a type of white blood cell responsible for fighting infections, play a critical role in AH. Patients with AH often exhibit an increased number of neutrophils.
Researchers are exploring the potential of targeted therapies to correct neutrophil dysfunction in AH. There is a focus on understanding the detailed transcriptional mechanisms of neutrophil dysfunction and the role of miR-223 in regulating the effects of neutrophils in liver disease.