SPOTLIGHT -
Maternal COVID-19 Vaccination, Infection Boosts Infant Antibody Response
Natural infection plus COVID-19 vaccination in pregnant mothers conferred more durable antibody responses in infants than natural infection alone.
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COVID-19 Vaccination in Children May Protect Against Long COVID
The findings may support further COVID-19 vaccination in children and reduce vaccine hesitancy.
Hepatitis B Reactivation Risk Low in People With HIV Following Antiretroviral Switch
The findings emphasize the importance of reviewing all hepatitis B serology reports prior to switching HIV treatment.
Blood Culture Algorithm Optimizes Bacteremia Diagnostics, Reduces Overtreatment
The algorithm sought to address high rates of false-positive cultures, excessive antibiotic use, and unnecessary diagnostic procedures in an emergency department setting.
Sulbactam-Durlobactam Effective Against Hospital-Acquired ABC Infections
The combination antibiotic was equally effective against both monomicrobial and polymicrobial Acinetobacter baumannii-calcoaceticus Complex infections.
Nirsevimab Shows Sustained Efficacy in Infants Through Full RSV Season
The monoclonal antibody demonstrated a significant impact on RSV-related hospitalizations regardless of infant characteristics.
Fostamatinib Helps Reduce Reliance on Oxygen in Severe COVID-19
Adding the oral therapy to standard of care helped reduce total days on oxygen for those hospitalized with COVID-19.
New Malaria Vaccine Endorsed by WHO Could Help Resolve Supply Issues
When implemented broadly, malaria vaccines can have a significant impact on public health.
FDA OKs Updated Novavax COVID-19 Vaccine
The updated emergency user authorization follows similar approvals and authorizations for Moderna and Pfizer's COVID-19 vaccines.
EMA Takes Up Positive Opinion of Remdesivir Use for COVID-19 in Patients With Liver Disease
The expanded indication to those with severe hepatic impairment has already been granted in the US and EU.
C Diff, COVID-19 Coinfection Risk Greatest in Older Women
Those with certain comorbidities, including peptic ulcer disease and renal failure, were at additional risk of developing C diff infection.
Vaccine Hesitancy Among the Top Barriers to Hepatitis Eradication
A global review demonstrates the potential depth of the impact of the COVID-19 pandemic on ongoing immunization delay and skepticism.
Late-Stage Trial in Chronic Hepatitis D Discontinued Due to Safety Concerns
Several trial participants experienced concerning hepatobiliary events.
FDA Approves Pfizer's Maternal RSV Vaccine Abrysvo to Protect Infants
The vaccine is intended to help prevent lower respiratory tract disease caused by respiratory syncytial virus in infants from birth to 6 months of age.
Bavarian Nordic's Chikungunya Vaccine Succeeds in Phase 3, Building Support for BLA
The vaccine is steps behind another Chikungunya vaccine candidate from Valneva, which is currently under priority review by the FDA.
GSK Claims Patent Infringement in Suit Against Pfizer's RSV Vaccine
The lawsuit comes as the RSV market is likely to get more crowded, with a pending approval for Pfizer's pediatric indication later this month and a BLA submission from Moderna recently filed.
NIH Names Jeanne Marrazzo, MD, to Lead National Institute of Allergy and Infectious Diseases
Marrazzo is currently the director of the Division of Infectious Diseases at the University of Alabama at Birmingham, and will assume her role at the NIAID in the fall.
Merck's Adult Pneumococcal Conjugate Vaccine Shows Promise in Phase 3 Trials
The vaccine targets an additional 8 unique serotypes that disproportionally affect the adult population.
RSV Vaccine Effective at Preventing Lower Respiratory Tract Infection in Older Adults
The investigational vaccine was effective in reducing both lower respiratory tract and all respiratory tract infections.
HCV Screening By Mail Effective Among VA Cohort
Distance to the clinic negatively impacted whether the HCV-positive individual attended their first HCV visit.