FDA PDUFA Date Set for C diff Drug, SER-109
The US FDA has accepted a Biologics License Application (BLA) for Seres Therapeutics' SER-109, and set a Prescription Drug User Fee Act (PDUFA) action date of April 26, 2023.
To Eliminate Hepatitis by 2030, Hepatitis B Needs More Attention
Experts are advocating for occult hepatitis B to be spotlighted.
Non-Targeted Screening Program Could Identify More HCV Infections
With an all-ready challenging patient population to treat, having a program to get more people into treatment can be helpful in an underserved group.
FMT Trial Halted Early Due to Clear Efficacy for Recurrent C Difficile
A fecal microbiota transplant (FMT) trial was halted early due to clear evidence the treatment was superior to placebo.
Higher Hepatitis Viral Load Increases Risk of Vertical Transmission
Among pregnant women coinfected with HIV, a higher hepatitis C viral load increased the likelihood of transmitting HCV to children.
HCV Not Associated With Myocarditis Risks for Young HIV Patients
However, according to one study the risk of heart inflammation increases with age and amplifies in patients with hepatitis C (HCV) compared to patients without HCV.
Greater Mortality and Disease Severity in Patients with Hepatitis B and COVID-19
A meta-analysis study shows having the comorbidity presents significant health risks for this patient population.
Hospitalized C Diff Patients May Pass Infection to Family
People exposed to a family member recently hospitalized with C difficile infection were 73% more likely to contract CDI themselves.
Better Sampling to Reduce C Difficile Misdiagnosis
Improving stool sample collecting and testing reduced C difficile underdiagnosis.
Universal Hepatitis B Vaccine Recommended by CDC
The federal agency's new guidelines for adults between 19-59 years replaces risk-based recommendations.
Engaging in Antimicrobial Stewardship Reduces Antibiotic Usage
Engaging in antimicrobial stewardship programs led to a reduction in antibiotic usage in long-term care facilities, potentially reducing the growing risk of antibiotic resistance.
Nursing Homes at Increased Risk of Antibiotic Resistant Infections
To reduce antimicrobial resistant pathogens, nursing homes should carefully monitor their use of hospital-grade antibiotics.
Hospitals That Use More Antibiotics Have More C Difficile Infections
Hospitals with lower c difficile antibiotic usage averaged shorter length-of-stay than hospitals that prescribed more antibiotics.
Lower BMI Increased Risk of C Diff Infection in Elderly Pneumonia Patients
Underweight elderly pneumonia patients were more likely to contract C difficile infection.
COVID-19 Patients Indicated for More Severe C Difficile Outcomes
COVID-19 patients were not at increased risk of Clostridium difficile infection. However, those already infected with C diff were more likely to experience severe outcomes.
Seqirus Granted FDA Approval for First Cell-Based Influenza Vaccine
The FDA has approved patients 6 months and older to receive Seqirus's first-ever adjuvanted, cell-based influenza vaccine.
Investigational Clostridioides Difficile Therapy Demonstrates Superiority Over Placebo
Ferring Pharmaceuticals and Rebiotix reported results from a trial on their therapy, RBX2660, which shows promise as a Clostridioides difficile infection (CDI) treatment.
Q&A With William Schaffner, MD, on the Lifting of Mask Mandates
A discussion with William Schaffner surrounding the CDC recently updating their recommendations on mask wearing.
Pediatric Appendicitis Patients More Likely to Suffer Additional C Diff Infection
The proportion of cases with CDI in perforated appendicitis was found to be greater in comparison to the non-perforated cases.
Risk of Infection With C Diff Found to Be Reduced With COVID-19 Measures
CDI prevalence among those hospitalized with a COVID-19 infection was not found to be increased despite more use of antibiotics.
Can C Diff Be Overlooked?
With labs blinding a specific panel, a C diff diagnosis can be masked and missed.
Similar Rates of Mortality Seen in Hospitalized COVID-19 Patients with Chronic Inflammatory Diseases
Hospitalized patients with COVID-19 and chronic inflammatory diseases were seen to have no statistically significant increased length of hospital stay or need for mechanical ventilation.
CDC Reports Adverse Events for Pfizer-BioNTech, Moderna COVID-19 Vaccines
With millions of mRNA vaccine doses administered, the US Centers for Disease Control and Prevention (CDC) provide information on these events.
Increase in Vaccine Distribution Announced by President Biden
Project aims for additional good-paying jobs, combatting the climate crisis, advancing racial equity, and building back better than before.
Pfizer COVID-19 Vaccine Anaphylaxis Report Released by CDC
The federal agency announces that of nearly 2 million vaccinations, only 21 total cases of severe reactions took place.
New Study Explores Link Between Hepatitis C and Atherosclerotic Cardiovascular Disease
A team of investigators review global HCV infection rates in an attempt to quantify HCV-associated cardiovascular disease.
Universal Hepatitis B Screenings for Pregnant Women Included in New Recommendations
The new recommendations aim to limit the potentially deadly disease from infecting newborns or mothers.
2 Clarke Drive Cranbury, NJ 08512