The Patient Impact of CDI, Preventing Reoccurrence
A clinician discusses the disease burden of reoccurring CDI, but sees a silver lining in the new investigational therapies potentially changing the treatment paradigm for the better.
The Next Big Thing in Stewardship?
A clinician is advocating for incorporating diagnostic stewardship practices within antimicrobial stewardship programs, which could someday lead to best practice guidelines on a larger scale.
Rapid Diagnostic Testing’s Impact on Timing to Optimal Therapy
Utilizing a newer technology, investigators wanted to see if a reduction in time led to clinically significant antimicrobial adjustments.
Measuring the Effectiveness of a Novel Antibiotic for Patients with Nontuberculous Mycobacterial Infections
A multicenter study looked at treating these infections with omadacycline.
Monoclonal Antibody ADG20 Neutralizes COVID-19 Variants
The investigational, fully human IgG1 monoclonal antibody ADG20 prevented and treated infection with COVID-19 variants of concern.
Monitoring Vancomycin Area Under the Curve Dosing
A medical center wanted to review prescribing and documentation practices for their pharmacists.
Investigating RBX2660 for Recurrent C Difficile Infection
RBX2660, an investigational microbiota-based live biotherapeutic for the treatment of C difficile, safely and effectively reduced recurrent C diff for 6 months.
Examining Oral Vancomycin as a First-Line CDI Therapy
With limitations on fidaxomicin at their facility, a hospital looked at vancomycin usage to determine if they needed to align with the new IDSA/SHEA CDI treatment guideline.
Assessing Vancomycin and Metronidazole Susceptibility for CDI
A team of investigators studied Clostridioides difficile infection (CDI) isolates to gauge resistance in the 2 antibiotics.
The Role of a Stewardship Pharmacist in Treating UTIs in the Outpatient Setting
A health system piloted a program that explored having an infectious disease pharmacist aid in guiding treatment.
Hospital Discharge a Key Opportunity to Practice Antimicrobial Stewardship
Designing a transitions of care stewardship program and engaging all stakeholders can help cut down on unnecessary antibiotic prescriptions.
Vancomycin With a β-Lactam: Comparing Acute Kidney Injury Rates of Trough vs AUC Dosing
Can clinicians rely on dosing strategy to avoid acute kidney injury for patients receiving vancomycin with a β-lactam like piperacillin-tazobactam?
Managing CDI in the Ambulatory Setting
Investigators sought information on how the infection is treated in outpatient clinics
Challenging Gram Negative Pathogens and Oral Carbapenems: MAD-ID Updates With Jason Pogue, PharmD
Jason Pogue, PharmD, BCPS, BCIDP, shares key takeaways from his 2 presentations at MAD-ID 2022, including a new alternative to the SPACE acronym, as well as how to navigate any anxieties around oral carbapenems.
Assessing Antibiotic Prescribing Patterns in Adult Primary Care Clinics
A MAD-ID 2022 poster sought to better understand the current antibiotic prescribing patterns at adult primary care clinics affiliated with Maimonides Medical Center in New York.
Tools to Ease Non-Infectious Disease Provider Comfort Prescribing PrEP
In a poster presented at MAD-ID 2022, Margaret Pertzborn, PharmD, evaluated the efficacy of a PrEP Provider Toolkit on non-infectious disease provider comfort prescribing PrEP with their patients.
The Role of Machine Learning in Evaluating Early and Cumulative Beta-Lactam for Inpatient Pneumonia
A study looked at the utilization of the technology with this antibiotic class in hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP).
Examining Clostridioides difficile Incidence and Clinical Impact Across the US
In a poster presented at MAD-ID 2022, Glenn S. Tillotson, PhD, FIDSA, FCCP, shares data from the Premier Healthcare Database on more than 100,000 patients with C diff.
Examining Candida Auris Susceptibility Patterns
AdventHealth Orlando studied a small number of these fungal isolates to examine treatment resistance patterns.
How the COVID-19 Pandemic Affected Antimicrobial Stewardship
At MAD-ID 2022, Payal K. Patel, MD, MPH, FIDSA, discussed how COVID-19 misinformation and lags in diagnostics contributed to inappropriate antibiotic use and offers some way to combat this trend.
Remdesivir Stewardship Reduces Hospital Stay Duration of COVID-19 Patients
In hospitalized COVID-19 patients, remdesivir stewardship reduced hospital length of stay and therapy duration.
Role of the Microbiome in Preventing Recurrent C difficile Infection
Colleen R. Kelly, MD, FACG, speaks at MAD-ID 2022 on alternatives to antibiotics for C diff infection, including the use of probiotics and fecal microbiota transplantation.
Antimicrobial Stewardship Pearls to Optimize Patient Outcomes: Matthew B. Goetz, MD
“Clearly, stewardship is a team operation. It starts [with] the leadership, the clinical pharmacy, and coordination with infectious disease physicians truly has to be synergistic,” Goetz said in the keynote address at MAD-ID 2022.
Antimicrobial Stewardship After Patient Discharge Is Lacking
Among community-acquired pneumonia (CAP) outpatients, 49% were prescribed unnecessary antibiotics.
Outcomes of Monoclonal Antibody Treatment in Hospitalized COVID-19 Patients
Leveraging antimicrobial stewardship programs was crucial to ensure COVID-19 hospital inpatients received monoclonal antibody therapy quickly and safely.
The Importance of Antimicrobial Stewardship in Patients Coinfected with COVID-19 and Sepsis
To reduce the risk of antimicrobial resistance, rapid laboratory diagnostics are needed to identify the pathogens in hospital patients with COVID-19 and sepsis.
MAD-ID: Dedicated to Antimicrobial Stewardship
The organization has its upcoming antimicrobial stewardship meeting in less than two weeks, and offers professional education and training in infectious diseases with a special emphasis on antimicrobial stewardship.
Shorter Prescription Stop Dates Do Not Influence Antibiotic Treatment Duration
An effort to increase stewardship showed that 5-day and 10-day prescription stop dates for antibiotics did little to influence actual therapy length and outcomes.
Antibiotic Prescribing, Guideline Adherence May Vary by Care Setting
An assessment from the Cleveland Clinic shows prescribing concordant to guidelines can exceed 60% in certain facilities.
Tocilizumab Could Treat Cytokine Release Syndrome in Severe COVID-19 Patients
The IL-6 targeting monoclonal antibody is linked to improved inflammatory and hemodynamic markers in hospitalized patients.
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