The latest CDC numbers show a 5.8% increase in measles cases from week-to-week, bringing the 2026 US total to more than double the amount seen in all of 2025 with 2 months left in the year.
|Articles|March 26, 2020
COVID-19 Treatment: Updates March 19-24, 2020
Erin K. McCreary, PharmD, BCPS, BCIDP; and Jason M. Pogue, PharmD, BCPS, BCIDP, provide an update of published literature on experimental treatments for COVID-19 from the past week.
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Clinicians and researchers across the globe are working with fervor to mitigate the world pandemic caused by SARS-CoV-2, the virus responsible for coronavirus disease 2019 (COVID-19). New data emerge daily, and it is imperative we embrace a deliberate calm to scrutinize the evidence and report it intentionally, despite our overwhelming desire to find an effective treatment. We
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* McCreary is an active member of the Society of Infectious Diseases Pharmacists and an infectious diseases clinical pharmacy at the University of Pittsburgh Medical Center.
**Pogue is the president of the Society of Infectious Diseases Pharmacist and a clinical professor at the University of Michigan College of Pharmacy.
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Investigational agent Zelicapavir cut time to complete RSV symptom resolution by up to a week and lowered hospitalization in high-risk adults.
Alejandra Gurtman, MD, discussed the phase 2 data at IDWeek 2026 which showed the investigational 25-valent pneumococcal conjugate vaccine 25vPnC produced serotype 3 antibody levels about 15-fold higher than Prevnar 20 after the booster dose, targeting a serotype still behind 10.6% of invasive pneumococcal disease in US children younger than five years.
The latest CDC numbers show a 4.0% increase in measles cases from week-to-week, bringing the 2026 US total to 4588 confirmed cases. Ninety-six percent of cases are outbreak-associated.
In the phase 3b ENCORE trial, adding amikacin liposome inhalation suspension (ALIS) to azithromycin and ethambutol significantly improved culture conversion in newly diagnosed MAC lung disease, while treatment-emergent amikacin (2.2%) and macrolide (1.1%) resistance stayed rare. Kevin Winthrop, MD, provides insights around the study.
Oral zelicapavir cut time to complete RSV symptom resolution by up to 1 week in high-risk adults, but it did not meet its primary end point in a phase 2 trial.
The latest CDC numbers show an 8.1% increase in measles cases from week-to-week, bringing the 2026 US total to 4410 confirmed cases. A CDC disease detective is going to Pennsylvania to aid in the state's massive outbreak, and the agency reports on a rare measles complication that is uniformly fatal.
An APP-driven complex outpatient antimicrobial therapy (COpAT) program for patients with bone and joint infections cut mean time to post-discharge follow-up from 20.1 to 9.7 days but did not significantly reduce 30-day readmissions or emergency department visits.
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