SPOTLIGHT -
Violence in Beni Continues to Impede Progress in Ebola Outbreak
Sixteen WHO health workers have been evacuated from the epicenter of the outbreak following an attack on their residence.
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Avoid All Romaine Lettuce, CDC Says
The CDC is advising all Americans to avoid romaine lettuce products until a source can be identified in an outbreak of Shiga toxin producing-E coli O157:H7 affecting 11 states and Canada.
FDA Accepts Supplemental NDA for Ceftazidime and Avibactam
The FDA has accepted a supplemental NDA that seeks to expand the label of ceftazidime and avibactam to include the treatment of cUTI and cIAI in children older than 3 months.
The Efficacy of Fecal Transplants for C diff
Sahil Khanna, MBBS, MS, discusses the efficacy of fecal transplants and new investigational candidates that are being evaluated in clinical trials.
PrEP Adherence Not Decreased by Substance Use in MSM
A study found that while MSM who have used stimulant or non-stimulant substances had increased rates of STIs, PrEP adherence was not decreased by substance use.
NAFLD Linked With Traditional Metabolic Risk Factors in People Living with HIV
A new study suggests in people living with HIV, metabolic risk factors including low HDL, hypertriglyceridemia and BMI were associated with nonalcoholic fatty liver disease.
Bacterial Pneumonia Linked With Increased Risk for Cardiac Events
In a study of nearly 5000 patients with pneumonia, those diagnosed with bacterial pneumonia had a 60% greater risk of a major adverse cardiovascular event.
CDC Investigates Multistate Salmonella Agbeni Outbreak with a Suspected Link to Cake Mix
The US Centers for Disease Control and Prevention (CDC) has announced the investigation of a Salmonella outbreak with a suspected link to Duncan Hines cake mix.
The Fight Against Resistance: Shorter is Better
Brad Spellberg, MD, highlights research that indicate shorter courses of therapy are safer and as effective as longer ones, as well as the importance of randomized controlled trials.
Is Ebola on the Path to Becoming Endemic in the DRC?
The current Ebola outbreak in the Democratic Republic of Congo has surpassed 300 cases and international health officials are now questioning if it is capable of being controlled.
Identifying Patterns of Comorbidities in People Living with HIV
A new study reveals that in people living with HIV, comorbidities occur in non-random patterns and appear to be correlated to one another, highlighting the complexity of multimorbidity patterns.
High Toxocara Egg Contamination Found in Areas of Pennsylvania Parks
Highest amounts of Toxocara egg contamination were in areas that could contain food droppings or animal waste.
Iclaprim Non-Inferior to Vancomycin in Treating Patients with Wound Infections
Data from a pooled analysis of the REVIVE-1 and 2 studies found iclaprim to be non-inferior to vancomycin based on earl clinical response in patients with wound infections.
Recalls You Should Be Aware Of—Week of October 28, 2018
We’ve rounded up a list of important US Food and Drug Administration (FDA) and US Department of Agriculture (USDA) recalls from this past week.
FLAIR Study Meets Primary Endpoint in Virally Suppressed Adults with HIV at 48 Weeks
ViiV Healthcare has announced that a long-acting injectable 2-drug regimen has met its primary endpoint in the FLAIR study of virally suppressed adults with HIV.
LATTE-2 Study Results Favorable at 160 Weeks
A long-acting injectable regimen of cabotegravir and rilpivirine has demonstrated high rates of virologic response, long-term durability, and good overall tolerability at 160 weeks.
More Prevention Research Needed to Control the HIV/AIDS Pandemic
In a plenary at the HIV Research for Prevention conference, Anthony Fauci, MD, discussed the need for implementation of new HIV prevention mechanisms.
Salmonella Newport Outbreak Linked to Ground Beef Springs Up in 22 States
The CDC is investigating an outbreak of Salmonella Newport that is suspected to be linked to contaminated ground beef products.
New Jersey Department of Health Investigates Adenovirus Outbreak
The New Jersey Department of Health has confirmed 18 cases of human adenovirus type 7 in pediatric patients.
Colorado Mumps Outbreak Emphasizes Importance of Community Partnerships in Response Efforts
In 2017, 47 outbreak cases of mumps were reported in the Denver Metropolitan area among individuals who attended Marshallese church events.
Global HIV Vaccine Enterprise Releases 5-Year Strategy to Develop HIV Vaccine
At the HIV Research for Prevention, in Madrid, Spain, the Global HIV Vaccine Enterprise presented a framework for working towards the development of a safe and effective HIV vaccine.
Recombinant Lassa Fever and Rabies Vaccine Shows Promise in Animal Models
The inactivated recombinant vaccine protected guinea pigs that were exposed to the Lassa virus 58 days post-vaccination.
29 States Affected by Multidrug-Resistant Salmonella Outbreak Linked with Chicken
Individuals in 29 states have fallen ill with Salmonella Infantis, which has also been detected in live chicken and chicken products from 58 facilities.
Security Concerns and Case Counts Rise As Ebola Outbreak Rages On
The new epicenter of the outbreak is the Beni Health Zone in which 66% of the new cases have been reported since September.
Health Officials in India Announce Third Zika Outbreak
The Government of India Ministry of Health and Family Welfare has announced 22 confirmed cases of Zika virus in Jaipur as of October 8, 2018.
Recalls You Should Know About Week of October 7, 2018
We’ve rounded up a list of recalls issued by the US Food and Drug Administration (FDA) and the US Department of Agriculture (USDA) from this past week.
Penicillin: Once Allergic Does Not Mean Always Allergic
Approximately 10% of US patients report having an allergic relation to penicillin, yet only 1% of the population are truly allergic.
Use of Oritavancin to Expedite Discharge Proves Cost-Effective in ABSSSI Patients
Cristen Whittaker, PharmD, explains the findings of an analysis that compared length of stay, readmission, and costs in patients with ABSSSIs who received oritavancin or vancomycin.
Comparison of Ceftolozane/Tazobactam vs Polymyxin/Amingoglycoside for Treatment of MDR/XDR Pseudomonas aeruginosa
Jason Pogue, PharmD, BCPS-AQID, discusses the need for real-world data to support Ceftolozane/tazobactam and shares the findings of his comparative study on using the regimen to treat MDR/XDR Pseudomonas aeruginosa.
RESTORE-IMI 1 Trial Compares IMI/REL and IMI+CST in Patients with Bacterial Infections
Keith Kaye, MD, presented the analysis of the RESTORE-IMI 1 phase 3 trial which evaluated imipenem/cilastatin/relebactam versus imipenem/cilastatin plus colistin.