SPOTLIGHT -
TANGO Study Meets Primary Endpoint at 48 Weeks
The phase 3 study is assessing whether a switch to dolutegravir plus lamivudine from TAF-containing HIV treatment regimens can successfully maintain viral suppression.
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California's Interventions Improve Kindergartner Vaccination Rates
Following the elimination of personal belief exemptions, the statewide rate of kindergartners without up-to-date status for required vaccinations decreased from 9.84% in 2013 to 4.87% in 2017.
US Measles Cases Taper Off After Record-Breaking Year
During the week ending July 3, 2019, 14 new cases of measles were confirmed, a sharp decline from the week ending on March 23, 2019, in which 87 new cases were confirmed.
Popular Dog Treat Linked to MDR Salmonella Outbreak
Forty-five cases have been documented in a multidrug-resistant Salmonella outbreak with a suspected link to contact with pig ear dog treats.
ACIP Updates Hepatitis A Vaccine Recommendations
The recommendations are currently under review by US Centers for Disease Control and Prevention and the Department of Health and Human Services.
Rate of Cryptosporidiosis Outbreaks Linked to Pools and Water Parks Growing
Outbreaks of the water-borne pathogen increased an average of 13% each year between 2009 and 2017.
Investigators Successfully Eliminate HIV in Mouse Model
The investigators used a combined approach of LASER ART and CRISPR-Cas9 to successfully eliminate replication-competent HIV-1 DNA from the genome of living mice.
1 Child Dead in Cluster of E coli Cases Linked to San Diego County Fair
Four children have been diagnosed with Shiga-toxin producing E coli following a visit to the San Diego County Fair during the month of June.
Dozens Sickened With Salmonella After Eating Papayas
CDC is warning consumers in several states to dispose of whole, fresh papayas imported from Mexico following the detection of a multistate outbreak of Salmonella Uganda.
Investigators Discover Antibody Capable of Inhibiting Multiple Strains of Norovirus
A single antibody, A1431, showed broad blockade toward tested GII.4 strains and was able to neutralize the pandemic GII.P16-GII.4 Sydney strain of norovirus.
Study Evaluates Delamanid as Prevention for People Exposed to MDR-TB
PHOENIx MDR-TB is comparing the safety and efficacy of delamanid, a new drug, with the older TB drug isoniazid for preventing active MDR-TB among individuals exposed to the disease.
A Summary of the 2018-19 US Flu Season
The 2018-19 US flu season lasted 21 weeks, marking the longest season in a decade.
Can Cannabidiol Fight Drug-Resistant Gram-Positive Bacteria?
Australian investigators conducted an assessment to determine if cannabidiol was effective at killing a range of gram-positive bacteria.
Survey Reveals Prevalence of Vaccine Misinformation
Survey results emphasize the value of educating full-time students with science- and health care-focused majors about vaccines.
Cluster of V Vulnificus Pops Up in Previously Non-Endemic Area
Vibrio vulnificus is a serious gram-negative pathogen that can lead to wound and intestinal infections and has high rates of mortality.
Uganda Authorizes Use of 3 Experimental Ebola Therapeutics
The neighboring nation to the DRC has also launched ring vaccination following the confirmation of 3 travel-associated Ebola cases.
ECHO Study: No Association Between HIV Infection and Contraceptive Methods
According to the study, the 3 contraceptive methods that were studied had high levels of safety and effectiveness in preventing pregnancy and well received by study participants.
Investigators Use Experimental Flu Drug to Cure Tick-Borne Virus in Mice
A team of investigators at Washington University School of Medicine used favipiravir to cure Bourbon virus in a mouse model.
FDA Issues Safety Alert on FMT Following Transmission of MDR Organisms
This warning comes after the FDA was made aware of bacterial infections caused by multidrug-resistant organisms have occurred following transmission during FMT.
USPSTF Gives PrEP a Grade A Recommendation for HIV Prevention
The HIV Medicine Association reports that the recommendation, once implemented in 2021, will require insurers to cover PrEP with no cost-sharing to patients.
Ebola Cases Confirmed in Uganda
This case is the first confirmed case of Ebola that Uganda has detected during the ongoing outbreak in the neighboring Democratic Republic of the Congo.
DRC Ebola Outbreak Tops 2000 Cases
As the DRC records 2000 cases of Ebola, Contagion® spoke with Krutika Kuppalli, MD, about how this outbreak is unique and whether there is an end in sight.
Ohio Hospital Searches for Source of Deadly Legionnaires' Outbreak
At least 8 cases of Legionnaires’ disease have been confirmed in an outbreak within an Ohio hospital that just opened on April 28, 2019
Yoav Golan, MD, on the Recent Approval of Ceftolozane/Tazobactam for HABP/VABP
Following the approval of the new indication, Contagion® spoke with Yoav Golan, MD, of Tufts University School of Medicine, to discuss the implications of the approval.
Chinese Social Platform Uses Geolocation to Promote HIV Testing in MSM
Following the launch of the campaign in March 2015, investigators saw a 77% increase in HIV testing compared with January and February of the same year in Beijing.
Remdesivir Shows Promise Against Nipah Virus in Monkeys
The experimental drug protected 4 African green monkeys following a lethal dose of Nipah virus in a study conducted by NIAID, CDC, and Gilead investigators.
CDC Warns US Could Lose Measles Elimination Status
Thus far 971 cases of measles have been documented in the United States in 2019.
HCV Testing and Treatment in Prisons Improves Outcomes, But At What Price?
Initiating a model that provides testing, treatment and linkage to care for HCV in correctional facilities would improve outcomes but requires a costly investment.
Baking Flour Stirs Up Controversy in Multistate E coli Outbreak
Investigators with the Rhode Island Department of Health discovered the outbreak strain in a bag of unopened flour sold by ALDI stores.
NJ Documents 5 Deaths in Ongoing Legionnaires' Disease Outbreak
According to the New Jersey Department of Health, there have been 22 confirmed cases of Legionnaires’ disease in individuals who reside in or visited Union County.