Sophia Abene

Joseph Zackular, PhD suggests that mRNA vaccines and monoclonal antibodies could offer more effective treatments for recurrent C difficile infections

Joseph Zackular, PhD, shares insights on his team’s mRNA vaccine research for C difficile, highlighting progress in animal models and future plans for human trials.

Health officials are investigating an outbreak called "Dinga Dinga," which causes fever and uncontrollable shaking.

This week, evolving COVID-19 inpatient care protocols with ECMO and remdesivir, FDA breakthrough designation for a rapid sepsis test, E coli outbreak linked to iceberg and romaine lettuce, and more.

The development of CRMA-1001, a potential functional cure for chronic hepatitis B and D, is set to enter clinical trials in 2025.

P aeruginosa is found in 11.6% of diabetic foot infection cultures from hot, humid climates.

Sexual transmission was confirmed for nine of the 22 viruses studied, including Ebola, Zika, and mpox, making it a key factor in ongoing disease spread.

Alba Azola, MD discusses the challenges of diagnosing and managing Long COVID and its overlap with ME/CFS, emphasizing the need for individualized care and ongoing research.

Navigating the long road of Long COVID involves more than recovering from an infection; it requires specialized, multifaceted care to address ongoing and often invisible neurological symptoms.

Interim findings from the STOMP trial reveal that tecovirimat does not significantly accelerate lesion resolution or reduce pain in mild to moderate mpox cases.

Study found that VRE colonization is linked to higher mortality, increased need for mechanical ventilation, and renal replacement therapy, while MRSA and C diff colonization showed less impact.

If confirmed by the CDC, these cases would increase the national total of human infections to 60, with 58 already reported in various states.

Hospitalization rates for RSV in children under five are comparable to pre-pandemic levels, with the highest rates observed in infants aged 0-2 months.

A multistate outbreak of E coli O157:H7 infections has been served at catering events, restaurants, and schools.

This week, a Mayo Clinic study found that removing C diff from gastrointestinal pathogen panels reduced unnecessary treatments, a Salmonella outbreak was linked to cucumbers, and a hepatitis C therapy achieved a 98% sustained virologic response in non-cirrhotic patients, among other developments.

Milad Zandi, PhD, on rising temperatures and the spread of mosquito-borne diseases like dengue, Zika, and chikungunya, increasing the risk of outbreaks in tropical and temperate regions.

Study explores the receptiveness to long-acting antiviral solutions in low- and middle-income countries.

Most outbreaks were caused by Cryptosporidium, a chlorine-resistant parasite, underscoring the need for stricter safety measures and better facility management.

The complex and often frustrating realities that patients face when dealing with a post-infection condition that remains misunderstood by many continue to unfold.

Nirsevimab proves effective in preventing RSV-related medical visits and hospitalizations in infants, with enhanced results in catch-up immunization programs.

Amesh A. Adalja, MD, FIDSA outlined the importance of recognizing antibiotic resistance in healthcare settings, educating patients on responsible antibiotic use, and the need for new treatments and diagnostic tools.

Raw milk products are not pasteurized, making them more susceptible to carrying harmful pathogens, in this case, bird flu.

Daniel Ilges, PharmD, BCIDP discussed this improved diagnostic stewardship, reduced unnecessary treatments, and had no impact on diagnosis timelines.

This week, GigaGen has launched a Phase 1 trial for GIGA-2339, a potential functional cure for chronic Hepatitis B, public health concerns like the California raw milk recall due to H5N1 and new findings linking lung dysfunction to cognitive decline in Long COVID patients, and more.

This study explores HLA-E as a target to activate the immune system in HBV infection, identifying a stable peptide, Env371-379 L6I, that effectively triggers T-cell responses.

New research using advanced MRI techniques explores how impaired pulmonary gas exchange may contribute to cognitive impairments in Long COVID patients, offering insights for potential treatment strategies.

CDPH advises consuming pasteurized milk, which kills the virus, while the state increases testing and monitoring following 29 confirmed human cases of H5N1 linked to infected dairy cows.

Using fecal microbiota transplantation within the CGA framework further enhanced survival and care efficiency.

Combining over 1,000 human antibodies, GIGA-2339 aims to achieve viral clearance and activate the immune system, offering a potential solution where current therapies fall short of providing a cure.

Recent studies show oral vancomycin reduces CDI by 64% in stem cell transplant patients, Biktarvy is effective for HIV/HBV co-infection, climate change drives rising dengue cases, and a 7-day antibiotic regimen is as effective as 14 days for bloodstream infections.