Identifying High-Risk Recurrent Clostridioides Difficile Patients for BezlotoxumabApril 18th 2022
The greatest risk factors for recurrent Clostridioides difficile infection (CDI) were age of at least 65 years, severe primary CDI, and use of non-CDI antibiotics. Patients with these risk factors should be prioritized for bezlotoxumab therapy.
Targeting a Key Marker of Clotting and Inflammation in COVID-19 PatientsFebruary 15th 2021
CalciMedica has developed Auxora, a calcium release-activated calcium (CRAC) channel inhibitor, and it has shown it can reduce the levels of D-dimer, a key biomarker associated with COVID-19 mortality.
Combination Therapy Using Remdesivir Shows Positive Effect on Mortality and Intubation in COVID-19 PatientsFebruary 11th 2021
Patients with severe COVID-19 experienced positive benefits reducing mortality and intubation rates when using the therapy along with Decadron and convalescent plasma.
Use of Respiratory Viral Panels Does Not Impact Clinical Outcomes in ICU PatientsFebruary 21st 2019
A study reports that a respiratory virus infection diagnosis was not linked with a decrease in antibiotic exposure and use of respiratory viral panels did not affect clinical outcomes.
Stewardship-Led Communication Improves Outcomes for Patients With Positive CulturesFebruary 21st 2019
Following implementation of stewardship program-guided blood culture communication process, the time to optimal therapy was 9.2 hours shorter for patients at Saint Luke’s Hospital.
Antibiotic Use Following Ventilation for RSV Linked to Shortened Clinical CoursesFebruary 19th 2019
Antibiotic prescription following ventilation in children with RSV-LRTI was associated with a 1.21-day shorter duration of ventilation and a 2.07-day shorter length of hospital stay.
Hospital-Onset Sepsis Twice as Deadly as Community-Onset Sepsis, Study FindsFebruary 19th 2019
Hospital-onset sepsis is twice as deadly as community-onset sepsis and increases the risk of death 3-fold, according to the results of a cohort study comprising 2.3 million adult patients.