The ratio of K. pneumoniae
to E. coli
was 11:1. Overall, the survey showed that clinical specimens from 1.3 patients per 10,000 hospital admissions had CPEs. Carbapenemase-producing K. pneumoniae
isolates also showed high resistance to last-line antibiotics.
According to the authors, the prevalence of CPEs varied greatly between countries, with the highest rates found in Mediterranean and Balkan countries.
“We found a clear association with health care,” they add, “since most isolates were either acquired in hospital, often associated with intensive care treatment, or isolated from patients with previous hospital admission.”
Acknowledging the encouraging commitment shown by all participants in this initiative, Dr Grundmann and colleagues emphasize that this study suggests that challenges in creating a widespread, enhanced sentinel surveillance for carbapenemase-producing Enterobacteriaeceae
can be overcome. The EuSCAPE initiative created a European network of national reference laboratories and expert laboratories to provide information for monitoring incidence and spread of carbapenemases among Enterobacteriaeceae,
as well as the spread of CPE.
“Strengthening infection control efforts in hospitals is crucial for controlling spread through local and national health care networks,” the authors conclude.
Dr. Parry graduated from the University of Liverpool, England in 1997 and is a board-certified veterinary pathologist. After 13 years working in academia, she founded Midwest Veterinary Pathology, LLC where she now works as a private consultant. She is passionate about veterinary education and serves on the Indiana Veterinary Medical Association’s Continuing Education Committee. She regularly writes continuing education articles for veterinary organizations and journals, and has also served on the American College of Veterinary Pathologists’ Examination Committee and Education Committee.
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