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Gender-Affirming Care in Persons Living With HIVGender-affirming hormone therapy (GAHT) therapy consists of administration of exogenous hormones and suppression of endogenous hormone production, with the goal of obtaining characteristics more congruent with an individual’s gender identity. Here is a review of these therapies and consideration for PrEP and the risks associated with HIV in this diverse population.
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Antibiotic Heteroresistance: What Is It and How Does It Impact Patients?Low-frequency resistant cells in bacterial isolates are challenging to detect and may contribute to unexplained treatment failure.
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Optimizing Management of Complicated UTIsAn expert in infectious diseases reviews best practices for improving personalized medicine when treating complicated urinary tract infections and highlights the importance of antimicrobial stewardship.
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Timeline for mRNA Vaccine Development for Rift Valley FeverCaryn Fenner and Petro Terblanche outline Afrigen's clinical trial plans, local partnerships, and vaccine pipeline.
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Tuberculosis Meningitis in an Immunocompetent PatientRead more about the case of a 71-year-old man who was admitted after presenting with cold-like symptoms for 3 weeks.
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35% of Evaluated Patients De-Labeled in Penicillin Allergy StudyAt MAD-ID 2025, Cadhan McFadden presents data from a multidisciplinary ambulatory care project using PEN-FAST scoring and oral challenges to improve antibiotic access and accuracy.
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Clinical Implications, Study Takeaways of Gepotidacin For Uncomplicated UTIsPamela Kushner, MD, offers insights on the newly approved antibiotic including its novel mechanism of action, the new criteria incorporated into the phase 3 studies, and what it means for her to have this treatment available.
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Key Takeaways on FMTs in the Treatment of CDIExperts provide practice pearls for educating patients on and using FMTs for the management of CDI.
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Daptomycin Resistance Among Enterococci Is a Growing Antimicrobial Resistance ThreatIn a world heavily focused on therapeutic options for multidrug-resistant gram-negative organisms, the emergence of antimicrobial resistance among enterococci is often an under-recognized risk.
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The Future and Resources in HCV CareExpert hepatologists discuss future developments in HCV that they are excited about and provide resources for new providers to get started on delivering HCV care.
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A Pioneer in Coronavirus ResearchIn a wide-ranging interview, Susan Weiss, PhD, talks about winning the ASM Lifetime Achievement award, her work on coronaviruses, and her concerns around federal government funding and how it may shake up and limit basic science research.
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In the Aftermath: Post-Hurricane InfectionsHurricane season is accompanied by an uptick in infectious diseases associated with environmental and water exposures.
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Azithromycin Helps Reveal a Malaria Parasite WeaknessSabrina Absalon, PhD, explains how antibiotic disruption of the apicoplast led to the discovery of PfAnchor, a key protein required for parasite division and survival.
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Measles: An Old Foe Has ReturnedTexas is experiencing its largest measles outbreak in 30 years and the Centers for Disease Control and Prevention's (CDC) Epidemic Intelligence Service is providing support there. Here is an overview on testing, disease presentation, and vaccination, as well as commentary on the public health impact of vaccine hesitancy, and the unintended consequences of the immunization program’s success.
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Climate Change Effects on Vector-Borne Disease: The Case of LymeWith evolving weather patterns, the natural habitat of ticks is expanding, and more people are becoming susceptible to them.
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Biden Administration Unveils HCV Initiative: A Significant Step Towards Public HealthThe federal government is working to provide greater access to testing and treatment.
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Daptomycin Resistance Among Enterococci Is a Growing Antimicrobial Resistance ThreatIn a world heavily focused on therapeutic options for multidrug-resistant gram-negative organisms, the emergence of antimicrobial resistance among enterococci is often an under-recognized risk.
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Antimicrobial Resistance: Cause for Concern and Optimism?Kenneth Lawrence, PharmD, discusses the global problem and the need for a layered, multifaceted approach to antimicrobial resistance (AMR) and some of the ongoing inroads and progress being made to address the medical issue.
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GAFFI Continues Efforts to Raise Awareness and Improve Fungal Diagnostic CapabilitiesGAFFI is addressing fungal diagnostic gaps by raising awareness, implementing models, and advocating for resource shifts, despite challenges in funding, infrastructure, and political support.
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A Psychiatrist’s View on the Immune-Brain ConnectionRobert C Bransfield, MD, continues to share how vector-borne infections may trigger psychiatric symptoms not through direct brain infection, but by disrupting immune signaling and gene expression.
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Disseminated Gonococcal Infection Complicated by Suspected Osteomyelitis of Humeral HeadGonococcal septic polyarthritis is an uncommon manifestation of N gonorrhoeae infection, but has increased by about 40% in recent years.
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Invivyd Tracks SARS-CoV-2 Evolution, Prepares for Future VariantsRobert Allen, MD, on variant monitoring, antibody development, and the company's long-term approach to patient care.
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Key Takeaways on FMTs in the Treatment of CDIExperts provide practice pearls for educating patients on and using FMTs for the management of CDI.
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Long-Acting Lipoglycopeptides for the Treatment of Severe InfectionsLong-acting lipoglycopeptides (LGPs) like dalbavancin, oritavancin, and telavancin were developed with extended half-lives, initially targeting acute bacterial skin and skin structure infections (ABSSSIs). However, recent studies have explored their potential in treating other infections, including infective endocarditis (IE), bone and joint infections (BJIs), and bloodstream infections (BSIs), offering an alternative to standard care and outpatient antimicrobial therapy.
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“Triple Therapy” Facing Triple ThreatClinicians provide an overview of intraamniotic infections and offer treatment strategies for these challenging infections.
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Outpatient Antimicrobial Stewardship: The Keys to Developing a Successful ProgramThis form of stewardship can reduce unnecessary antibiotic prescribing, reduce costs, and optimize patient outcomes.
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Immune Deficits in Some Valley Fever Patients Hinder Response to Antifungal TreatmentResearch into new antifungal treatments, including drugs in phase two and three trials, offers hope for patients who do not respond to current therapies.
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Clinicians Discuss the State of Vaccines TodayA panel discusses how vaccine policy under new federal government policies, why misinformation has flourished and what individual providers can do to win back patient trust.
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The Impact of Widespread RSV Vaccination and Quantifying ResultsIn the fourth and final episode, the clinicians speak of the need for greater uptake of the RSV vaccines, overcoming an "RSV identity crisis," and the potential ancillary benefit of reducing bacterial infections.
