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Challenges in the Management of Mycobacterium abscessus ComplexThis pathogen is the third most frequently isolated nontuberculous mycobacteria seen in the United States. Here is a review of how it presents and treatment options.
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Supporting Patients With HIVAdvice to community physicians regarding ways to enhance patient-provider relationships and navigate barriers that impact the management of HIV infections.
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Correcting the Lack of Diversity in Clinical Trials With Community-Based StudiesAmmara Mushtaq, MD, discusses the underrepresentation of different races during the pandemic, but also the newer efforts to include and represent these communities in smaller, local studies.
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Optimizing Antibiotic Use by Limiting Total Antibiotic ExposureShorter durations of antibiotic therapy demonstrate similar efficacy and may improve safety compared with longer courses for certain infections.
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Reduced-Dose Trimethoprim-Sulfamethoxazole Effective in Treating Mild to Moderate Pneumocystis jirovecii PneumoniaHere is a review of using this therapy in this patient population.
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In These COVID 19 Times, Can We Reduce Hospitalizations Due to Skin Infections?Shortages of health care workers and an increase in COVID-19 cases has put a severe strain on the health care system. Thus, the opportunity to reduce the hospitalizations for other conditions and expand outpatient treatment opportunities should be welcomed.
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Reducing Peripheral Venous Catheter InfectionsLack of data may mean bloodstream infections caused by PVCs are an overlooked cause of morbidity in hospitalized patients.
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Final Diagnosis: Pott Puffy Tumor With Subdural EmpyemaA rare case of Pott puffy tumor occurs in an atypical patient with no risk factors, likely due to untreated sinus infection.
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Evaluating Safety and Efficacy of Vaxart's Oral Vaccine's Impact on COVID-19 VariantsPart 2 with James F Cummings, MD, as he discusses the need for a stronger response to emerging variants, the importance of protecting high-risk populations, and the potential to reduce vaccine hesitancy through easier administration.
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“Triple Therapy” Facing Triple ThreatClinicians provide an overview of intraamniotic infections and offer treatment strategies for these challenging infections.
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The Underlying Threat of Multidrug-Resistant Pathogens in the COVID-19 EraOver half of patients admitted with positive SARS-CoV-2 testing received antibiotics, but evidence of bacterial infection is uncovered in far fewer cases. We may already be seeing the effects of antibiotic overprescribing.
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Biden Administration Unveils HCV Initiative: A Significant Step Towards Public HealthThe federal government is working to provide greater access to testing and treatment.
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Shifting to Shorter Courses of Antibiotic Therapy for Common Pediatric InfectionsIn the latest SIDP column, two clinicians provide information on recent studies and guidelines directed at antibiotic durations in this patient population.
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A Common Health Habit May Lower Rates of Pneumonia, ICU MortalityThe data from these meta-analyses highlight the value of developing systems to promote daily toothbrushing among those who have been hospitalized and, particularly, those on mechanical ventilation.
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Sepsis Awareness Month: Highlighting the Findings from BLINGIIIContinuous antibiotic infusions show positive results and may improve outcomes for patients with severe sepsis.
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Differentiating Between DNA and mRNA PlatformsAmi Patel, PhD, provides insights on both technologies and how her research center, the Wistar Institute, is involved in DNA vaccine and monoclonal antibody research.
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Sticking It to COVID-19: The Expansion of the Pfizer-BioNTech Vaccine EUAA review of the data and circumstances that led to authorization in children ages 5 to 11 years.
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So You Made the Decision to Implement Vancomycin AUC Dosing. Now What?Since the vancomycin guideline update, institutional leaders have been faced with the challenge of implementing and monitoring AUC-guided dosing.
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Final Diagnosis: Donor-Derived Staphylococcus Iugdunensis Endocarditis of Transplanted Heart"This case gives uncomfortable insight into a gap in early detection of infections in immunocompromised, high-risk patient populations. "
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Supporting Universal HCV Screening Over Risk-Based TestingA new study finds that 1.4 million people aged 12-59 with current hepatitis C (HCV) infection, including over a third of them without a history of injection drug use.
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Preparing for the Next Long-acting AntiretroviralsClinicians can make room for infrequent treatment options as patients enjoy their daily lives.
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Epidemiology of C. difficile Infections in the USA panel of experts provide an overview of the epidemiology of Clostridioides difficile infections, highlighting diagnostic practices and the role of antimicrobial stewardship.
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COVID-19 Impact on Antimicrobial Stewardship: Consequences and Silver LiningsThis crisis has united multidisciplinary groups and laid the foundation to better equip the health care workforce for future pandemics.
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Combination Hepatitis C Therapy Efficacious in Those With Previously Untreated Acute InfectionTreatment with glecaprevir/pibrentasvir (G/P) demonstrated a virologic response at post-treatment week 12, which was superior to the prior efficacy threshold.
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Starting an Inpatient Penicillin Skin Testing Service in 2023Patients with a penicillin allergy can be safely delabeled using minimal resources, opening up treatment options.
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All About the JUICE: Justifying Use of Non-Carbapenems for Infected NeCrotizing PancrEatitisManagement of this condition has been associated with antibiotic misuse. In the latest Bench to Bedside column, clinicians offer insights on therapy indications and what the latest literature reports on the condition.
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The Role of Rifampin in Bone and Joint InfectionsIn the latest column from the Society of Infectious Diseases Pharmacists (SIDP), here is a discussion on the use of rifampin as an adjunctive antibiotic treatment for patients with diabetic foot osteomyelitis.
