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Discussing Outpatient COVID-19 TreatmentsHere is a look at some of the treatment alternatives, which can offer simpler logistics and cost considerations.
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Bioaccumulation of Drugs by Human Gut Bacteria Can Affect Drug AvailabilityA new study demonstrated that gut organisms can alter drug availability by biotransformation on a significantly broader scale than previously expected.
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Gender-Affirming Care in Persons Living With HIVGender-affirming hormone therapy (GAHT) therapy consists of administration of exogenous hormones and suppression of endogenous hormone production, with the goal of obtaining characteristics more congruent with an individual’s gender identity. Here is a review of these therapies and consideration for PrEP and the risks associated with HIV in this diverse population.
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Influenza Virus Is Primed for Continual Emergence and Pandemic PotentialThe broad host range and natural reassortment of the influenza virus has played an instrumental role in previous pandemics, and the virus is poised for future large-scale outbreaks.
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Climate Change Effects on Vector-Borne Disease: The Case of LymeWith evolving weather patterns, the natural habitat of ticks is expanding, and more people are becoming susceptible to them.
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Disseminated Gonococcal Infection Complicated by Suspected Osteomyelitis of Humeral HeadGonococcal septic polyarthritis is an uncommon manifestation of N gonorrhoeae infection, but has increased by about 40% in recent years.
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Precision Dosing of To-Marrow: Linezolid Therapeutic Drug MonitoringEmerging literature suggests therapeutic drug monitoring for this antimicrobial to minimize the risk for linezolid-associated toxicities while maintaining efficacy in select populations.
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COVID-19 Booster Shots and the FutureKey opinion leaders provide some advice for the public regarding COVID-19 booster shots and look to the future of the pandemic.
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Restoring Hope by Restoring Gut Flora: Rebyota and the Future of Combating Recurrent CDIAlthough fecal microbiota, live-jslm (Rebyota; RBX2660) is the first fecal microbiota product approved by the FDA, there are other microbiota-based agents in the pipeline.
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COVID-19 Booster Shots and the FutureKey opinion leaders provide some advice for the public regarding COVID-19 booster shots and look to the future of the pandemic.
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Final Diagnosis: Pott Puffy Tumor With Subdural EmpyemaA rare case of Pott puffy tumor occurs in an atypical patient with no risk factors, likely due to untreated sinus infection.
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Our Price for Not Aiming Higher: Long COVID Is Here to StayGuest author Seth Lederman, MD, calls Long COVID "one of the most pressing global health threats I have seen since fighting HIV/AIDS."
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Disseminated Gonococcal Infection Complicated by Suspected Osteomyelitis of Humeral HeadGonococcal septic polyarthritis is an uncommon manifestation of N gonorrhoeae infection, but has increased by about 40% in recent years.
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Community-Acquired Candida Glabrata Empyema: An Atypical Diagnosis Not to MissAlthough this patient had none of these common risk factors associated with Candida empyema, she did have other factors predisposing her to fungal colonization and subsequent infection.
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Daptomycin as Frontline Therapy for MRSA Bacteremia: Has the Time Come?Findings increasingly suggest the mortality risk may be reduced by initiating daptomycin within 3 days of infection.
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Practice Pearls for Treatment of Respiratory InfectionsTina Tan, MD; Wendy Wright, DNP, ANP-BC, FNP-BC, FAANP, FAAN, FNAP; Priya Nori, MD; Jacinda Abdul-Mutakabbir, PharmD; and Kevin Michael Reiter, MD, PA, provide key takeaways from the discussion on the treatment of respiratory viral infections.
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Amped-up Enterobacterales DebateDemystifying clinical data for treating invasive AmpC-harboring Enterobacterales.
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Impact of Inpatient Pharmacist Review of Discharge AntibioticsA food for thought as an ambulatory antibiotic stewardship initiative.
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Ready, Set, Cabenuva: Implementing Cabotegravir/RilpivirineThis novel therapeutic option represents the first long-acting injectable approved for maintenance of HIV-1 suppression.
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The Next Generation of COVID-19 Vaccines and BoostersWill there be an answer to keep the continuously evolving virus at bay? Are seasonal combination vaccines the wave of the future?
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Looking Toward the Future of CDI ManagementClosing out their discussion on Clostridioides difficile infection, panelists share closing thoughts on novel pipeline therapies.
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Increase in Enteroviruses Seen with Decreases in COVID-19 PrecautionsThe Centers for Disease Control and Prevention (CDC) reports the rise in pediatric acute respiratory illnesses especially as there is a decrease in hygiene measures that were previously employed during the pandemic.
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Daptomycin as Frontline Therapy for MRSA Bacteremia: Has the Time Come?Findings increasingly suggest the mortality risk may be reduced by initiating daptomycin within 3 days of infection.
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COVID-19–Associated Fungal Infections During EMCO: Review of Epidemiology, Diagnosis, and PharmacotherapyExamining pharmacological management in COVID-19 patients with ARDS requiring antifungal therapy during extracorporeal life support.
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Getting Help from HAL: Applying Machine Learning to Predict Antibiotic ResistanceA pair of experts assess literature on the means of interpreting hospitalized patient antibiotic resistance through machine learning.
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To Prophylax or not to Prophylax: Preventing CDIClinicians look at optimal approaches for trying to avoid Clostridioides difficile infection (CDI).
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Top 5 Tips for Teaching ID LearnersThe latest article from SIDP offers a Top 5 list of how to precept a learner on an infectious disease rotation.
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Combination Antifungal for Invasive Mucormycosis: Yay or Nay?There is limited and conflicting data regarding the role of combination antifungal therapy for treatment of invasive mucormycosis.
