Antibiotics

Researchers from the University of Bristol have revealed the structural and mechanistic basis of transferable colistin resistance conferred by the MCR-1 gene.

Elizabeth Nolan, PhD, and her team at the Massachusetts Institute of Technology, recently explored the fight between microbes and hosts over essential metals and how understanding this battle may open the door for alternate treatments for bacterial infections.

University of Connecticut researchers have developed novel antibiotic compounds to target methicillin-resistant Staphylococcus aureus infections, offering a potential new drug in the fight against this pathogen.

Researchers uncover high rates of co-infections in patients who are admitted to hospitals with influenza.

With cases of antibiotic-resistant gonorrhea on the rise, researchers from the University of York may have made a breakthrough in the quest to find treatments that work.

Research on a patient with acute myeloid leukemia has revealed new information on how bacteria mutate to survive antibiotics.

A new study has revealed more information on how microbes confer resistance to antibiotics.

A new study takes a look at the efficacy of off-label treatments for Clostridium difficile (C. difficile) infection.

A new study from University of Copenhagen researchers explains how some multidrug-resistant bacteria are able to survive lethal doses of antibiotics through a hibernation-like defense mechanism.

Researchers from the University of Würzburg in Germany discuss the use of marine natural products to fight drug-resistant pathogens.

With an increasing number of Salmonella infections showing resistance to antibiotics, a CDC team set out to determine which strains are most problematic.

Researchers shed light on how oxylipins play a key role in forming the biofilm shield that helps protect disease-causing bacteria against antibiotics.

A new study reveals evidence that a longer course of antibiotics is more effective for treating ear infections in young children.

Following a recent unanimous decision by United Nations General Assembly member states, the intergovernmental organization has announced it will be holding a high-level meeting in 2018 on the fight against tuberculosis (TB), the first-ever meeting of its kind.

An alternative antibiotic treatment regimen for multidrug-resistant tuberculosis (TB) endorsed by WHO shows promising effects in a new study using computer modeling.

In a new study, a team of pediatric hospital researchers found that cutting unnecessary blood cultures in children avoids false positives without resulting in missed sepsis diagnoses.

In a review article, researchers share current understanding of the pathogenesis of type IV T cell-dependent immune-mediated ADRs and review the evidence for diagnostics for T cell-mediated ADRs.

New guidelines released by researchers with the Infectious Diseases Society of America recommend that people with suspected latent tuberculosis infections receive a new generation of diagnostic testing.

Rita Olans, DNP, CPNP-PC, APRN-BC, assistant professor at MGH Institute of Health Professions, discusses how Infectious Disease specialists, pharmacists, and nurses can work together on antimicrobial stewardship.

A recent study examines antibiotic prescribing patterns in children in primary care settings in the United Kingdom, Netherlands, and Italy.

As antibiotic-resistant Pseudomonas aeruginosa infections continue to vex healthcare settings, a new study from University of Georgia researchers offers insight on just how the pathogen works inside the human body.

John Mohr, PharmD, president and founder of Medical Affairs Strategic Solutions, LLC, discusses push and pull incentives that drive antibiotic development.

Microbes found in New York City park soil samples contain an array of microbes capable of producing known pathogen-fighting compounds, along with a large number of recently discovered compounds.

John Mohr, PharmD, president and founder of Medical Affairs Strategic Solutions, LLC, discusses global and national initiatives for the development of new antibiotics.

Researchers from the University of California-San Francisco tested the ability of 2,177 FDA-approved compounds to reduce viral proliferation in Zika-susceptible cells.

John Mohr, PharmD, president and founder of Medical Affairs Strategic Solutions, LLC, explains the economics of antimicrobial development.

Public Health England and the Department for Environment, Food and Rural Affairs researchers in the United Kingdom found drug-resistant E. coli in a large number of chicken samples, while much lower rates of contamination were observed in beef and pork samples.

Lauri A. Hicks, DO, captain, US Public Health Service, director, Office of Antibiotic Stewardship, medical director, Get Smart: Know When Antibiotics Work, Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, examines the threat that antibiotic resistance poses to modern medicine.

A recent study lead by researchers from the University of Freiburg analyzed the occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in European hospitals.