C. Difficile

Minnie Hatch was in her late teens when she was diagnosed with the infection. Since then, she has had recurrent episodes and dealt with care challenges along the way.

Vedanta Biosciences initiates the Phase 3 RESTORATiVE303 clinical trial, marking a pivotal moment in the battle against this recurrent infection.

This week, a strategic approach along with existing treatments aimed at reducing incidence rates and curing people of HCV, advocating Lyme disease research in honor of May being its awareness month, Digestive Disease Week coverage, and more this week from Contagion.

At Digestive Disease Week, Paul Feuerstadt MD, FACG, AGAF and fellow investigators explore the potential impact of non-antibiotic medications on gut health and their association with recurrent CDI.

Antimicrobial stewardship to reduce multidrug resistance and opportunistic Clostridioides difficile infection (CDI) could also guide shorter treatment.

This week, new WHO data illustrates challenges during the acute phase of the COVID-19 pandemic, MAD-ID and ACVR conference coverage, and more from Contagion.

In patients with Clostridium difficile infection (CDI), ibezapolstat was shown to have similar results to a standard of care therapy.

Insights from Dr. Md Zahidul Alam on treatments and prevention strategies for C difficile infection (CDI), supported by the CDC's recent study on CDI management in healthcare settings.

Check out the latest studies, management strategies, patient advocacy, and other important news involving this condition.

A study presented at ESCMID aims to understand ribotype 955 as a new challenge in C difficile management.

A study presented at the Society for Healthcare Epidemiology of America (SHEA) conference assesses the link between antibiotic use and C difficile infection in Tennessee.

A study, presented at the Society for Healthcare Epidemiology of America (SHEA) conference, assesses laxative administration before CDI testing in Veteran Affairs (VA) hospitals and explores the demographic and contextual factors with non-adherence to guidelines.

Incidence of hospital-onset Clostridioides difficile infection differed between hospitals that implemented the CDC prevention strategies and those that did not, but not necessarily because of the strategies.

This annual event hosted by The Peggy Lillis Foundation (PLF) released their full agenda for advocacy and education that will be happen next week in Washington DC.

Community acquired pneumonia is often inappropriately diagnosed in hospital admissions, particularly among older adults with dementia, and can lead to in-hospital antibiotic-associated adverse events, such as Clostridioides difficile.

A study on the impact of guidelines on reducing hospital-onset CDI incidence.

FDA authorizes Ito Invivyd’s pemivibart (Pemgarda), insights on Sofosbuvir levels in pregnant women, the effectiveness of fidaxomicin vs vancomycin for CDI treatment, and more this week from Contagion.

Here is a review of the effectiveness of fidaxomicin vs vancomycin for CDI treatment in populations with immunocompromised conditions.

This week learn more about CDC's strategies to reduce waterborne diseases; the US change to a trivalent influenza vaccine; new data for Merck's pneumococcal vaccine; and how PCR testing can influence a patient diagnosis and outcome.

The impact of polymerase chain reaction (PCR) testing on patient outcomes.

Successful phase 2 trial leads to phase 3 trial towards managing C difficile.

This week, the FDA-approved antiretroviral lenacapavir as it showed treatment benefits; Oral Vancomycin Prophylaxis was explored for preventing C difficile in stem cell transplant recipients; Research into the after-effects of SARS-CoV-2 (PASC) uncovers biomarkers for post-infection sequelae; Chronic hepatitis B worsens COVID-19 outcomes, and cabotegravir ultra-long-acting (CABULA) has shown positive results.

Study dives into the complexities of using Oral Vancomycin Prophylaxis to combat Clostridioides difficile in hematopoietic stem cell transplantation recipients with insights from researcher Alexander Vartanov, MD.

The American Gastroenterological Association recommends fecal microbiota-based therapies for recurrent or severe C difficile infections and other gastrointestinal issues.

This week, increased risk of long COVID in individuals who have tested positive for the virus, advancements in the preservation of the microbiome offer new strategies for healthcare-associated infections (HAIs), FDA-approved GSK's bepirovirsen signaling the company's goal to cure viral hepatitis, CDC considers changing 5-day COVID isolation guideline, and the first victim of the Alaskapox virus highlights the critical need for increased research into emerging infectious diseases.