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GASTROINTESTINAL INFECTIONS

The organizations set out 3 recommendations for initial and recurrent C diff treatment.

IDSA, SHEA Announce New Clostridioides Difficile Clinical Guidelines

During the COVID-19 surge last year, the federal government stopped the required reporting on healthcare-associated infections (HAI) thus leaving an absence of data and important information on HAI. One study examined the effect the initial pandemic surge had on Clostridioides Difficile infection (CDI) in one hospital. 

How Did COVID-19 Affect Clostridioides Difficile Testing and Incidence Rates?

An assessment of the frontline agents show similarities infection cure and recurrence rates at 30 days.

Stem Cell Patients with C Difficile Benefit from Vancomycin, Fidaxomicin

Ferring Pharmaceuticals and Rebiotix reported results from a trial on their therapy, RBX2660, which shows promise as a Clostridioides difficile infection (CDI) treatment.

Investigational Clostridioides Difficile Therapy Demonstrates Superiority Over Placebo

A study looked at hospital admissions of Medicare patients and saw a large percentage of recurrent Clostridioides difficile infections (rCDI) as the primary diagnosis.

The Burden of Clostridioides Difficile

An effort to increase stewardship showed that 5-day and 10-day prescription stop dates for antibiotics did little to influence actual therapy length and outcomes.

Shorter Prescription Stop Dates Do Not Influence Antibiotic Treatment Duration

A large retrospective analysis of Medicare patients offers a glimpse of the incidence rates of this patient population and the burdens associated with it.

Understanding Recurrent Clostridioides Difficile Infection and Hospitalization 

A meta-analysis suggest the 2 first-line C diff therapies provide similar outcomes, yet differ in recurrent infection risk.

Fidaxomicin, Vancomycin Provide Similar C Difficile Initial Cure, Mortality Rates

Cancer patients are more than twice as likely to acquire hospital-associated Staphylococcus aureus bacteraemia (HA-SAB) and Clostridioides difficile infection (HA-CDI) than others, a new study from Australia found.

Hospital-Associated SAB, CDI More Than Twice as Likely Among Cancer Patients

The proportion of cases with CDI in perforated appendicitis was found to be greater in comparison to the non-perforated cases.

C. DIFFICILE