New Freeze-Drying Technique Could Help Get Polio Vaccine to Remote Areas
Freeze-drying vaccines enables health officials to get vaccines to remote areas, but until now, it has not been possible for the fragile polio vaccine.
Test for Newborn Cytomegalovirus Infection Approved by FDA
The new test is approved to assist with detecting cytomegalovirus in newborns less than 21 days of age.
With Polio Eradication On the Horizon, Health Officials Tread Carefully
Polio could soon be completely eradicated, but public health officials have an intricate set of steps to ensure a lasting defeat.
This Halloween, Vaccine-Preventable Diseases Are All Trick and No Treat: Public Health Watch
New outbreaks of rubella and troubling data on influenza highlight the importance of vaccination.
Antivirals to Treat Herpes Infection May Decrease Risk of Dementia
Herpes simplex virus type 1 is associated with a higher risk of Alzheimer’s disease, yet the antivirals prescribed to treat the infection may reduce the risk of dementia.
Woman's Wound Infection Caused By Burkholderia thailandensis
A recent report has described a case of wound infection with the bacterium Burkholderia thailandensis in a woman in Arkansas.
Treatment of Antibiotic-Resistant Infections: Back to the Future of Therapies
The stage may finally be set for the phage therapy era for recalcitrant bacterial infections.
Study Provides Real-World Support for Single-Dose Oritavancin For ABSSSIs
Results indicate patients who received single-dose oritavancin were significantly less likely to be hospitalized, compared to those who received multidose vancomycin.
Increasing Duration of Surgical Prophylaxis Does Not Decrease Odds of SSI
Instead, increasing duration of postoperative antimicrobial prophylaxis is associated with higher odds of acute kidney injury and C diff infection in a dose-dependent manner.
Cardiac or Vascular Disease Not a Barrier to Delafloxacin For Treatment of Skin and Skin Structure Infections
Delafloxacin was found to be relatively safe and well tolerated in patients with acute bacterial skin and skin structure infections with past or present cardiac or vascular difficulties.
HIV-Positive Patients at Higher Risk of Late Mortality Following Cryptococcal Infection
Nonadherence to antiretroviral therapy was associated with a higher risk of death.
In Small Corner of Alzheimer's Research, 'Germ Theory' Begins to Gain Traction
Plenty of research has gone into the causes and progression of Alzheimer’s disease. Now a new effort aims to make the case that scientists have been looking in the wrong direction.
Iclaprim Proves Effective for ABSSSIs in Patients with Diabetes With Fewer Adverse Effects
Patients with diabetes who were treated for acute bacterial skin and skin structure infections (ABSSSIs) with iclaprim had fewer adverse events (AEs) than those who were treated with vancomycin, according to the results of a recent study.
The Rise of Resistant Staphylococcus epidermidis
Common skin bacteria have gained resistance to multiple antibiotics.
Investigational Rezafungin Shows In Vitro Activity Against Azole-Resistant Aspergillus
Rezafungin, an investigational antifungal, demonstrated significant activity against Aspergillus in an in vitro study.
Measles Outbreak and Malicious Actors in Europe: Public Health Watch
A social media campaign initiated in Russia may be sowing the seeds of debate surrounding vaccine safety, causing new outbreaks of measles globally.
Use of Oritavancin as Outpatient Treatment for ABSSTIs Generates Potential Cost Savings at Community Hospital
Additional evidence supports the use of oritavancin as a cost-saving outpatient treatment for acute bacterial skin and skin structure infections (ABSSTIs) in patients who would otherwise be admitted to the hospital for therapy.
Innate Immune System Prioritizes Lung Infections Over Wound Healing
In a wounded mouse model concurrently infected with influenza A, investigators observed that the innate immune system prioritized responding to the lung infection, delaying wound healing.
Smallpox—A Nightmare We Cannot Shake
There is a new treatment for this old disease, so why are we still worried?
Dimorphic Fungal Pathogen May Be Causing Fatal Infections in Western US and Canada
New geographical spread of the disease may warrant increased vigilance among labs and clinicians.
FDA Accepts NDA & Grants Priority Review for Iclaprim to Treat ABSSSIs
The PDUFA action date has been set for February 13, 2019.
FDA Advisory Committee Recommends Approval of Omadacycline For Treatment of CABP & ABSSSI
The FDA advisory committee voted 17 to 1 in favor of omadacycline for treatment of ABSSSI and 14 to 4 for the treatment of CABP.
Vibriosis Cases Prompt Calls for Summer Water Activity Safety
Following cases of vibriosis in New Jersey, Alabama, and Florida, health officials are telling individuals with open wounds to stay out of coastal or brackish waters.
Smallpox Treatment Moves Closer to FDA Approval
Development of the drug has been deemed necessary because of the potential for the use of the virus in a bioterrorism attack and waning herd immunity against the virus among the general population.
Study Shows Sulfonamide Antibacterials Capable of Reversing Azole Resistance in Candida albicans
Preliminary studies provide convincing evidence for the synergistic use of sulfonamide agents with azole antifungals.
New Research Reinforces Efficacy of Plazomicin
Research presented at the 2018 ASM Microbe Meeting has reinforced the value of the just-approved next-generation aminoglycoside antibiotic, plazomicin, in treating multidrug-resistant Enterobacteriaceae.
It Takes Two to TANGO With a Carbapenemase
Because of the global rise in antimicrobial resistance, meropenem-vaborbactam, the first carbapenem/β-lactamase combina­tion medication, is a welcome new antibac­terial.
Skin and Soft Tissue Infections on the Decline, Yet Still High Among Patients with HIV
Skin and soft tissue infections appear to be on the decline in the general population, but individuals with HIV have a higher risk.
Transition to Oral Therapy for the Treatment of Bacteremic Urinary Tract Infections
Several recent studies provide valuable insight surrounding the appropriateness of transitioning from intravenous to oral therapy when treating bacteremic urinary tract infections.
Future of OPAT for ABSSSI
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