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Although azithromycin or another antibiotic is given to an estimated one of four preschool-age children in emergency departments for wheezing episodes, it failed to demonstrate benefit in a new multi-center trial.

In the second episode of the series with Perry N. Halkitis, PhD, MS, MPH, he brings his personal experience to this topic and questions if there should be a shift in who manages the primary care needs of these patients.

The federal agency gave the nod for the smallest once-daily single tablet regimen available for virologically suppressed adults with HIV, including those on complex regimens. The approval is based on the results of the 2 phase 3 ARTISTRY trials.

The FDA has approved formulations for the 2026-2027 vaccines including Pfizer-BioNTech's Comirnaty XFG, Novavax's commercial partners Sanofi and Takeda have secured approvals for its Nuvaxovid, and Moderna's Spikevax and mNEXSPIKE vaccines, all with protections against the currently circulating variant.

The FDA has approved Pfizer-BioNTech's 2026-2027 Comirnaty XFG formula, an updated COVID-19 vaccine targeting the XFG variant, for adults 65 and older and for individuals ages five through 64 with at least one high-risk underlying condition.

Gavin Harris, MD, provides some context around what is happening in the Democratic Republic of Congo regarding the outbreak including the country’s inherent challenges as well as discussing the latest in testing, vaccines, and treatments of this rare strain of Ebola.

Venky Soundararajan, PhD, co-founder and chief scientific officer of nference, explains what the semaglutide-COVID-19/influenza data can and can't tell clinicians about mechanism, bias, and the evidence bar before it should shape prescribing.

The federal agency gave the nod to dolutegravir (Tivicay PD), making it the first second-generation integrase inhibitor cleared for children with HIV weighing at least 2 kg, including eligible newborns.

A retrospective cohort study of more than 29 million patients found adults with prior semaglutide use had significantly lower 30-day mortality, hospitalization, and acute kidney injury after COVID-19 or influenza infection compared with a metformin comparator group.

The phase 3 priMe trial found the investigational vaccine did not demonstrate noninferiority for preventing tuberculosis infection, though the study authors cited surrogate end point and exposure-imbalance issues that complicate interpretation.

Federal health officials are tracking simultaneous multistate outbreaks tied to frozen organic blueberries sold at Publix and alfalfa sprouts sold under the Calco and Everything Sprouts brands, together sickening more than 65 people across roughly 20 states.

Histoplasma, Blastomyces, and Coccidioides remain underrecognized causes of community-acquired pneumonia, particularly when clinical presentation mimics bacterial disease. Knowing where to look and when reshapes the diagnostic and therapeutic approach.

The US childhood vaccine schedule was the big news this month with the presidential executive order making changes to it as well as the latest Centers for Disease Control and Prevention kindergarten immunization numbers for the 2025-2026 year. Learn more about the news with clinician commentary and how it might impact patient care.