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Nonventilator Hospital-Acquired Pneumonia: Epidemiology, Prevention, and Where It Is NowThe management of hospital-acquired pneumonia requires use of preventive bundles, mitigative of risk factors, and prompt diagnosis with initiation of treatment when highly suspected.
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What We Know But Still Have to Learn About Long COVIDDespite advances in understanding and treating Long COVID, many questions about its mechanisms, susceptibility, and varied recovery patterns remain unresolved, underscoring the need for continued research.
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Do We Have New Data for Optimal Treatments of Candida-Related Prosthetic Joint Infections?The choice between debridement and implant exchange affects treatment outcomes for Candida-related prosthetic joint infections, highlighting the need for standardized guidelines and further research.
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Clinical Considerations in Conducting Antifungal Susceptibility TestingAccess to antifungal susceptibility testing (AFST) remains limited in the United States. Therefore, providers must recognize clinical situations where AFST will provide its greatest value. In the latest article from SIDP, infectious disease pharmacists offers some insights on this subject.
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A Case of Mycobacterium Chimaera Infective EndocarditisNonspecific, nondolent symptoms make this disease difficult to diagnose.
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A Review of the Currently Available Monoclonal Antibodies for COVID-19Outside of vaccines, these underutilized therapies are the best defense against severe disease.
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Celebrating 30 Years: The Past, Present, and Future of the Society of Infectious Diseases Pharmacists (SIDP)Introducing “Bench to Bedside With SIDP,” a new column covering everything from antimicrobial stewardship and pharmacokinetics/pharmacodynamics to mentorship, preceptorship, and more.
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A Viral Colonial Legacy: HIV, Monkeypox Emerged Due to Ongoing Colonial Viral NeglectSimilar to HIV, the colonial and postcolonial history is fundamental to the biology of this monkeypox outbreak.
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Merck's Clesrovimab Shows Effectiveness in RSV Prevention for InfantsAnushua Sinha, MD, discussed the findings, highlighting a 60.4% reduction in medically attended lower respiratory infections and significant decreases in RSV-related hospitalizations.
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SPREADing the Love: The Importance of Mentorship in PharmacyIn the latest column from SIDP, the authors discuss having leaders to help navigate school and beyond.
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Restarting Therapy in Patients with HIVAddressing patients with HIV who have fallen out of care, Shauna Applin, ARNP, provides clinical insights on treatment options and best practices for restarting therapy.
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Tuberculosis Meningitis in an Immunocompetent PatientRead more about the case of a 71-year-old man who was admitted after presenting with cold-like symptoms for 3 weeks.
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Tips for Talking with Patients about Fecal Microbiota Transplant for Recurrent C. difficile InfectionsTo close the discussion, experts on C. difficile infections discuss how they talk with patients about fecal microbiota transplantation.
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A Case of Varicella-Zoster Meningitis Causing Postoperative Fevers After Umbilical Hernia RepairDue to worsening headaches and unrevealing cross-sectional imaging and ascites fluid analyses, this patient's differential evolved toward a central nervous system source.
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Are We at a Breaking Point for Adoption of Updated Susceptibility Interpretive Criteria?The implementation of new College of American Pathologists rules presents an opportunity for collaboration between clinical microbiology laboratories and infectious disease pharmacists and physicians.
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Ceftriaxone Dosing: Once or Twice Daily?In the latest column from SIDP, clinicians discuss that along with the once-daily dosing for many indications, there are also compelling indications for twice-daily dosing.
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Early Experience With the BioFire Pneumonia PanelA balance between antimicrobial stewardship and the search for multidrug-resistant organisms.
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Honoring Her Daughter’s Legacy After a Long-Standing Battle With Antimicrobial ResistanceAfter Diane Shader Smith lost her daughter, Mallory, to a multidrug resistant infection, she turned her personal tragedy into a mission designed to inform people about antimicrobial resistance (AMR), and have the public coalesce around this expanding medical issue.
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Ethical and Innovative Use of AI in Infectious DiseasePatient-centered innovation amidst evolving regulations and policies is a key strategy.
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Increase in Enteroviruses Seen with Decreases in COVID-19 PrecautionsThe Centers for Disease Control and Prevention (CDC) reports the rise in pediatric acute respiratory illnesses especially as there is a decrease in hygiene measures that were previously employed during the pandemic.
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Tips for Talking with Patients about Fecal Microbiota Transplant for Recurrent C. difficile InfectionsTo close the discussion, experts on C. difficile infections discuss how they talk with patients about fecal microbiota transplantation.
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A Chance to Improve Hepatitis C Care for PWIDHere is a review of an opportunistic treatment approach to HCV infection in this patient population in a European study and some of the potential challenges in applying it in the United States.
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Imdusiran for Chronic Hepatitis B Achieves Functional Cure in 50% of PatientsArbutus CEO Michael McElhaugh discussed trial results showing that a combination of imdusiran, an RNAi therapeutic, and pegylated interferon alfa-2α can achieve a functional cure in chronic hepatitis B patients.
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High-Resistance Therapy Options for Treatment-Naïve Patients With HIVJoseph Eron, MD, Daniel R. Kuritzkes, MD, and Monica Gandhi, MD, MPH, discuss the likelihood of other combination regimens for the treatment of multidrug-resistant HIV, including monoclonal antibodies.
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Resolution of Scurvy in a Patient With a Spinal Cord InjuryAt 7.1%, vitamin C deficiency in the US is rare. Unfortunately, identifying scurvy is complex, frustrating, and time-consuming for both patient and provider.
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INSTIs and Cardiovascular Outcomes: More ComplexityThe significance of antiretroviral therapy (ART) has been a game changer for people living with HIV (PLWH). Still, there are some cardiovascular risks associated with different ART classes—particularly protease inhibitors (PIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs), and integrase strand transfer inhibitors (INSTIs). Authors review a piece in the literature around this area of study.
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Oral Therapeutic Options to Prevent Disease Progression From COVID-19 in an Ambulatory SettingAs the number of COVID-19 cases continues to rise, oral treatment options for at-home use are in demand to provide early intervention and reduce the progression to severe disease, hospitalization, and death.
