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Bacteriophage-Antibiotic Combinations: A Promising Alternative for Refractory Infections?Despite the initial abandonment of bacteriophages in most areas of the world, the era of antibiotic resistance has led to a resurgence of phage therapy in clinical practice.
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How Close Are We to a Cure for HIV?Evolving research has led the infectious diseases community to redefine its definition of cure.
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Salt, Ticks, and Lyme: A Case of Lyme Neuroborreliosis Presenting as SIADHThis case report is the fourth documented case of Lyme-induced syndrome of inappro­priate secretion of antidiuretic hormone (SIADH).
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Reduced-Dose Trimethoprim-Sulfamethoxazole Effective in Treating Mild to Moderate Pneumocystis jirovecii PneumoniaHere is a review of using this therapy in this patient population.
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Biosurveillance: A Critical Tool for Emerging and Reemerging Infectious DiseasesBiosurveillance is an essential early warning system for detecting and responding to infectious disease threats, helping to prevent localized cases from becoming widespread outbreaks or pandemics. Despite its proven value during crises such as COVID-19, biosurveillance programs often suffer from inconsistent funding and support, underscoring the urgent need for sustained investment and integration into public health infrastructure.
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"Antibiotic Never Events": The Ideal Target to Reduce Antimicrobial ExposureBy stopping unnecessary antibiotics before they start, clinicians can avoid unnecessary harm to the patient and the population.
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Antiretroviral Stewardship: The Time is NowIn this narrative review of studies evaluating antiretroviral stewardship programs (ARVSPs), we propose core elements for ARVSPs that are based on published evidence, clinical experience, and adapted from antimicrobial stewardship programs.
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National HIV Testing Day: Free Screening Services Available at WalgreensTesting and information will be available at select Walgreens stores in more than 260 cities on National HIV Testing Day on Thursday between 10 am and 7 pm.
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E-cigarette Users, Especially Women, May Be More Susceptible to FluEarly research found that e-cigarette use affects the immune system response to the flu virus and the effects are different for female and male users.
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Wiki-What? Navigating WikiGuidelines and Leveraging Their AdvantagesWikiGuidelines produces novel clinical practice guidelines developed with pragmatic, applicable methodology, including a diverse author group.
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"Antibiotic Never Events": The Ideal Target to Reduce Antimicrobial ExposureBy stopping unnecessary antibiotics before they start, clinicians can avoid unnecessary harm to the patient and the population.
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A Case of Varicella-Zoster Meningitis Causing Postoperative Fevers After Umbilical Hernia RepairDue to worsening headaches and unrevealing cross-sectional imaging and ascites fluid analyses, this patient's differential evolved toward a central nervous system source.
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Treating HCV in HIV-Coinfection: Still a Therapeutic Dilemma?Despite the availability of highly active agents against HCV, HIV-infected patients require special considerations for drug interactions when considering treatment options.
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Site-Specific Labeling Provides New Insight on Influenza Virus VariationA new method assessing the influenza A strain provides investigators with a more detailed look at influenza viruses.
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Vancomycin Loading Doses Improve Target Timing and Safety in 61,000+ CasesAt MAD-ID 2025, Tiffany Lee, PharmD, presents multi-center findings showing no increase in AKI with higher initial dosing.
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Individualized Beta-Lactam Therapy and MonitoringElevated beta-lactam concentrations have been associated with neurotoxic adverse effects, including seizures and mental status changes.
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A Chance to Improve Hepatitis C Care for PWIDHere is a review of an opportunistic treatment approach to HCV infection in this patient population in a European study and some of the potential challenges in applying it in the United States.
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Those With HIV Shown to Have More Coronary PlaqueEven if HIV-positive individuals have a low-to-moderate risk for cardiovascular disease, they still experience more coronary plaque.
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10 Key Pillars to an Effective Ebola ResponseEVD outbreaks this year serve as a reminder of the virus’ severity and the importance of having a containment strategy in place.
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Intravenous Antimicrobials: Is It Time to Push?Intravenous (IV) push is an attractive option to administer antimicrobial therapy to patients in an efficient and effective manner in a variety of clinical settings. While many advantages to IV push administration exist, clinicians should be mindful of available literature regarding safety profiles, pharmacokinetic/pharmacodynamic characteristics, and clinical data for IV push antimicrobial administration prior to utilizing it in specific patient populations.
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Oral Therapeutic Options to Prevent Disease Progression From COVID-19 in an Ambulatory SettingAs the number of COVID-19 cases continues to rise, oral treatment options for at-home use are in demand to provide early intervention and reduce the progression to severe disease, hospitalization, and death.
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Navigating Long COVID and ME/CFS OverlapAlba Azola, MD discusses the challenges of diagnosing and managing Long COVID and its overlap with ME/CFS, emphasizing the need for individualized care and ongoing research.
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Daptomycin as Frontline Therapy for MRSA Bacteremia: Has the Time Come?Findings increasingly suggest the mortality risk may be reduced by initiating daptomycin within 3 days of infection.
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Oral Vancomycin "Tail" Offers No Added Benefit for CDI ProphylaxisAt MAD-ID 2025, Jiye Park, PharmD, presents findings showing once-daily dosing is effective, with no added benefit from extended vancomycin use after antibiotics.
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Protecting Older Adults From Severe COVID-19Allergist and immunologist Juanita Mora, MD, urges vaccination, masking, and outreach to safeguard vulnerable communities.
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Combating Misinformation on AntimicrobialsInsights from Catherine Bertrand Ferrandis, DVM, on the role of One Health and interdisciplinary collaboration.
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Phase II Study Shows Efficacy of 6-Month Regimen of Lenacapavir, Teropavimab, and Zinlirvimab for HIVOnyema Ogbuagu, MBBCh, FACP, FIDSA discussed 96% virologic suppression with lenacapavir-based therapy, showing similar results to daily oral regimens.
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Challenges and Implications of the V Quinn TB Prevention TrialGregory Fox, PhD outlines the trial's challenges, the impact of combining results with the TB Champ trial, and the role of collaboration in strengthening research outcomes.
