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Antibiotics Ranked by Risk for Serious Cutaneous Adverse ReactionsStudy ranks antibiotic classes by risk for rare, life-threatening cutaneous reactions of Stevens-Johnson syndrome and toxic epidermal necrolysis.
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HIV Treatment Advice for Community PhysiciansExperts provide community physicians treating HIV with practical advice for screening, diagnosing, and managing patients with HIV.
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Bringing Culture-Independent Diagnostic Tests for Bloodstream Infections Into Rational Patient ManagementThese tests have the potential to transform patient care and antimicrobial stewardship, but they have not gained widespread acceptance, partly because of uncertainty over how to use them clinically.
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SVR Possible in PWID Infected With Hepatitis C Virus Despite Imperfect Adherence to TreatmentPeople who inject drugs who are infected with hepatitis C virus can achieve sustained viral response, despite imperfect adherence, according to the results of a new trial.
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Hepatitis C Saliva Tests May Show a False-Negative Result if HIV Is Also PresentSaliva tests for detecting HCV infection may not be the best option for determining infection status.
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Utah's Public Health Approach to Recent Hepatitis A OutbreakIn May 2017, a case of hepatitis A was detected in a Salt Lake County hospital. Over the next 20 months, Utah health officials worked to address what ended up being the largest hepatitis A outbreak in the state’s history.
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Bacteriophage-Antibiotic Combinations: A Promising Alternative for Refractory Infections?Despite the initial abandonment of bacteriophages in most areas of the world, the era of antibiotic resistance has led to a resurgence of phage therapy in clinical practice.
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How Close Are We to a Cure for HIV?Evolving research has led the infectious diseases community to redefine its definition of cure.
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Salt, Ticks, and Lyme: A Case of Lyme Neuroborreliosis Presenting as SIADHThis case report is the fourth documented case of Lyme-induced syndrome of inappro­priate secretion of antidiuretic hormone (SIADH).
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Reduced-Dose Trimethoprim-Sulfamethoxazole Effective in Treating Mild to Moderate Pneumocystis jirovecii PneumoniaHere is a review of using this therapy in this patient population.
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H5N1: The Outbreak the US Got Bored WithSince its detection in early 2024, H5N1 has spread to dairy cows, poultry, and wild birds. Political factors, including leadership changes at the Centers for Disease Control and Prevention and cuts to public health resources, have worsened the situation, leading to a weakened response.
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"Antibiotic Never Events": The Ideal Target to Reduce Antimicrobial ExposureBy stopping unnecessary antibiotics before they start, clinicians can avoid unnecessary harm to the patient and the population.
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Antiretroviral Stewardship: The Time is NowIn this narrative review of studies evaluating antiretroviral stewardship programs (ARVSPs), we propose core elements for ARVSPs that are based on published evidence, clinical experience, and adapted from antimicrobial stewardship programs.
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National HIV Testing Day: Free Screening Services Available at WalgreensTesting and information will be available at select Walgreens stores in more than 260 cities on National HIV Testing Day on Thursday between 10 am and 7 pm.
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E-cigarette Users, Especially Women, May Be More Susceptible to FluEarly research found that e-cigarette use affects the immune system response to the flu virus and the effects are different for female and male users.
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Wiki-What? Navigating WikiGuidelines and Leveraging Their AdvantagesWikiGuidelines produces novel clinical practice guidelines developed with pragmatic, applicable methodology, including a diverse author group.
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"Antibiotic Never Events": The Ideal Target to Reduce Antimicrobial ExposureBy stopping unnecessary antibiotics before they start, clinicians can avoid unnecessary harm to the patient and the population.
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A Case of Varicella-Zoster Meningitis Causing Postoperative Fevers After Umbilical Hernia RepairDue to worsening headaches and unrevealing cross-sectional imaging and ascites fluid analyses, this patient's differential evolved toward a central nervous system source.
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Treating HCV in HIV-Coinfection: Still a Therapeutic Dilemma?Despite the availability of highly active agents against HCV, HIV-infected patients require special considerations for drug interactions when considering treatment options.
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Site-Specific Labeling Provides New Insight on Influenza Virus VariationA new method assessing the influenza A strain provides investigators with a more detailed look at influenza viruses.
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Vancomycin Loading Doses Improve Target Timing and Safety in 61,000+ CasesAt MAD-ID 2025, Tiffany Lee, PharmD, presents multi-center findings showing no increase in AKI with higher initial dosing.
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Individualized Beta-Lactam Therapy and MonitoringElevated beta-lactam concentrations have been associated with neurotoxic adverse effects, including seizures and mental status changes.
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A Chance to Improve Hepatitis C Care for PWIDHere is a review of an opportunistic treatment approach to HCV infection in this patient population in a European study and some of the potential challenges in applying it in the United States.
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Those With HIV Shown to Have More Coronary PlaqueEven if HIV-positive individuals have a low-to-moderate risk for cardiovascular disease, they still experience more coronary plaque.
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10 Key Pillars to an Effective Ebola ResponseEVD outbreaks this year serve as a reminder of the virus’ severity and the importance of having a containment strategy in place.
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Intravenous Antimicrobials: Is It Time to Push?Intravenous (IV) push is an attractive option to administer antimicrobial therapy to patients in an efficient and effective manner in a variety of clinical settings. While many advantages to IV push administration exist, clinicians should be mindful of available literature regarding safety profiles, pharmacokinetic/pharmacodynamic characteristics, and clinical data for IV push antimicrobial administration prior to utilizing it in specific patient populations.
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Oral Therapeutic Options to Prevent Disease Progression From COVID-19 in an Ambulatory SettingAs the number of COVID-19 cases continues to rise, oral treatment options for at-home use are in demand to provide early intervention and reduce the progression to severe disease, hospitalization, and death.
