Coronavirus / COVID

A quartet of candidates will be simultaneously assessed in younger and older healthy adult patient groups in the phase 1/2 trials.

The wearable technology is now authorized to monitor patients for changes in QT interval. Investigational drugs being administered to COVID-19 patients, such as chloroquine and hydroxychloroquine, can cause prolongation of QT intervals and life-threatening arrhythmias.

Michael B. Edmond, MD, MPH, MPA, MBA, explains his hypothesis that universally adopting face shields could help cut the transmissibility of COVID-19.

Virologists have taken marketed drugs from in-vitro screening for potential to repurpose for SARS-CoV-2 to in-vivo results in animal model.

Even after putting public health policies in place, the state reached 2600 nursing home cases before the end of April.

A team of investigators lay out 3 scenarios for the global pandemic duration—based on previous pandemic learning and public health adherence.

Cornelius J. Clancy, MD, discusses navigating partial trial information and the need for coherent national coordination on the COVID-19 response.

Midway through the pandemic outbreak, investigators attempts to highlight some of the strongest candidates to fight the disease.

The test reports ≥99.8% specificity and 100% sensitivity at 14 days post-PCR confirmation, and could potentially better inform patient immunity and disease pathology.

Commentary outlines “best practices” for studies looking into possible treatments, vaccine.

Contagion Editor in Chief Jason Gallagher, PharmD, discusses the new authorization for the controversial antiviral therapy.

The decision comes shortly after conflicting human trial results assessing the intravenous antiviral drug.

A brief summary of our daily COVID-19 coverage.

Stay up-to-date on the latest infectious disease news by checking out our top 5 articles of the week.

In a study of patients in China, investigators found most men were more likely than women to have severe cases of COVID-19, and more likely to die from the disease.

Children who were confined to their homes due to the COVID-19 outbreak in Hubei province, China, reported higher rates of depressive symptoms and anxiety.

The FDA has added a ventilator developed by NASA to the list of authorized ventilators.

Studies should be done in humans to gain insight, before making recommendations solely on lab results, the study authors said.

A round up of the top infectious disease news from April.

Half of surveyed hospitals have no ventilator triage policies, and existing policies differ substantially and often lack guidance on implementation.

"Operation Warp Speed" seeks to develop and disburse 100 million doses of a COVID-19 vaccine to the public by year’s end.

A review of our latest COVID-19 coverage.

If half of Americans eventually get infected with the novel coronavirus, the US healthcare system could face costs of more than $400 billion, a new study finds.

Treatment with remdesivir was not associated with statistically significant clinical benefits. However, the numerical reduction in time to clinical improvement in those treated earlier requires confirmation in larger studies.

Michael K. Gusmano, PhD, discusses the importance of maintaining ethical standards in research evaluating potential therapeutics and vaccines for COVID-19.