HCV / Hepatitis

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This year at the Conference on Retroviruses and Opportunistic Infections (CROI), Lenacapavir shows virological suppression, Remdesivir reduces long covid risks, Bulevirtide benefits chronic HBV, HIV treatment enhances outcomes, vaginal ring or oral pre-exposure prophylaxis safe for HIV prevention throughout pregnancy.

In thinking about the international and national public health campaigns to eliminate hepatitis, is general awareness of the disease enough to motivate treatment-hesitant hepatitis patients to accept clinical care, or does there need to be a greater commitment beyond that?

This week, a study advocates enhancing hospital cleaning protocols to halt healthcare-associated infections; integrating HCV testing and antivirals in prisons to cut transmission of the disease; FDA announces listeria outbreak that leads to deaths and hospitalizations across 11 US states; CDC makes advances in foodborne outbreak detection via genome sequencing; and new data about the self-amplifying mRNA vaccine, ARCT-154.

This week, a measles outbreak spans multiple US states and the CDC highlights a rise in syphilis incidents. Fatalities from Group A strep infections have doubled since last year in Canada, and people who inject drugs are at higher risk for hepatitis C and HIV. Investigators are also tracking incident rates over time post-COVID-19 pandemic.

This week CDC discusses vaccine recommendations; a provider offers insights on administering live biotherapeutics; and early administration of simnotrelvir plus ritonavir shortened the time to sustained resolution of COVID-19 symptoms.