California Governor Proclaims State of Emergency for Monkeypox
The aim is to increase vaccination rates and awareness in the state with the second most confirmed cases.
FDA Provides PDUFA Date for Ibrexafungerp
This regulatory review is for the prevention of recurrent vaginal yeast infections. And if approved, it would be a second indication for the antifungal related to these infections.
Biktarvy Effective for HIV Patients Coinfected With Hepatitis B
At AIDS 2022, Gilead presented data suggesting Biktarvy was a safe and effective complete HIV treatment regimen, including for those coinfected with hepatitis B.
Longer Interval Between COVID-19 Vaccine Doses May Cut Risk of Myocarditis or Pericarditis
The highest rate of myocarditis or pericarditis after mRNA COVID-19 vaccination occurred among young men ages 18 to 24 after receiving a second dose of the Moderna vaccine.
New York State, San Francisco Declare Monkeypox Emergencies
Public health officials made the decision after seeing increasing incidence rates.
Middle East, North Africa Face Emerging HIV Epidemics With Lagging Response
HIV epidemics are emerging among key populations in the Middle East and North Africa, and the region ranks lowest globally in response indicators.
Regular COVID-19 Screening in Schools Can Control Infections, Limit Closures
The model suggests screening unvaccinated students could reduce absences by 80% compared to reactively closing classes with infected students.
WHO Outlines Antibiotic Development Priorities
With antimicrobial resistance a rising threat, the World Health Organization is working to heighten awareness of the urgent need for new therapies.
COVID-19 Vaccine Boosters: Benefits, Expansion of Eligibility, and Mixing and Matching of Vaccines
Clinicians offer insights on a variety of elements surrounding boosters.
World Hepatitis Day: Where Do We Go From Here?
What steps need taken to end viral hepatitis by 2030? “It all comes down to testing,” said Carl Schmid, executive director of the HIV+Hepatitis Policy Institute.
Association of Adenovirus with Hepatitis of Unknown Cause in Children
Implicating adenovirus for hepatitis of unknown cause in children is confounded by its absence in some cases, and from all tested hepatic tissue.
“Increased Screening, More Outreach, More Support”: Ending Viral Hepatitis
Viral hepatitis “can and should be managed within primary care,” says Dr. Thomas Robertson.
Pulmonary Coinfection With C neoformans and C immitis: A Novel Fungal Cohabitation
A patient presented with a history of uncontrolled HIV and a history of polysubstance use.
World’s First HIV-Positive Heart Transplant Performed Successfully
An HIV-positive woman in her 60s has recovered from a simultaneous heart and kidney transplant.
Oral Carbapenems: Promise, Peril, and Pushbacks
Here is a review of the literature for this class of antibiotics.
IV Push Administration for Outpatient Parenteral Antimicrobial Therapy
Investigators designed a quasi-experimental pre- and post-intervention analysis comparing a pre-intervention cohort receiving IV drip antibiotic infusion with a post-intervention cohort receiving IVP administration.
Recurrence Escalates Financial Burden of CDI
Frequent recurrence of Clostridioides difficile infection drives up financial burdens of the disease and underscores the need to improve access to treatment, infection prevention, and new therapies.
WHO Declares Monkeypox Virus a Global Health Emergency
Last weekend, the World Health Organization declared the monkeypox viral outbreaks a Public Health Emergency of the International Concern (PHEIC).
Bioaccumulation of Drugs by Human Gut Bacteria Can Affect Drug Availability
A new study demonstrated that gut organisms can alter drug availability by biotransformation on a significantly broader scale than previously expected.
Oral Carbapenems Are Failing to Break Through
A Day in the Life of a Public Health Professional
As the pandemic enters its third year, fatigue and frustration grow, but there is hope for the future.
Trying to Reduce AMR Through Legislative Means
Working to Fight AMR is working in Washington DC to help pass policies in Congress to help alleviate this significant issue.
PrEP State of the Union: Adherence, Access, Uptake Issues
Although this form of prophylaxis is highly protective, there are situations in which breakthrough infections occur.
Antimicrobial Stewardship: More Is Better
A robust stewardship program requires a comprehensive investment in technology and staff.
COVID-19 Antibodies After 1 and 2 Pfizer Vaccine Boosters
This Israeli study found 3 and 4 doses of Pfizer-BioNTech bolstered antibody titers in adults 60 and older.
CDC Issues Health Advisory for Parechovirus in Infants
The CDC is advising clinicians to test for parechovirus in infants exhibiting fever, sepsis-like syndrome, or signs of neurological impairment.
President Biden Tests Positive for COVID-19
He is experiencing mild symptoms and is going to take Paxlovid.
Rickettsial Infections Heat Up in the US
With the warmer months in full swing, here are clinical considerations and strategies for tick-borne infections.
Potential Monkeypox Treatments May Already Exist
As monkeypox cases increase, investigators are turning to smallpox antivirals.
Cefiderocol’s Role in Managing Carbapenem-Resistant Acinetobacter baumannii Infections
This agent is likely best utilized as part of a combination when treating this bacterium but data regarding appropriate combinations are scarce.